Name: Ditophal
Brand: TargetMol
SKU: T219041
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 mg

待询

10-14周

50 mg

待询

10-14周

生物活性

产品描述	Ditophal is an orally effective thiol ester compound used as an anti-tuberculosis and anti-leprosy agent. It is effective against Mycobacterium tuberculosis infections, both subcutaneous and intracerebral, in guinea pigs, including strains resistant to isoniazid. Ditophal alters the staining properties of Mycobacterium leprae, reducing the bacterial index of leprosy. At high doses, subcutaneous administration in guinea pigs can cause ulcers at the injection site. Ditophal is utilized in research on tuberculosis and leprosy.
体内活性	Ditophal（100–200 mg/kg；口服；每日2次；共90天）可降低经皮下感染 Mycobacterium tuberculosis 的豚鼠器官结核病变严重度评分，并延长存活时间。Ditophal（10–50 mg/kg；皮下注射；每日或每周；共120天）同样可降低经皮下感染 Mycobacterium tuberculosis 的豚鼠器官结核病变严重度评分并延长存活时间。对于脑内感染 Mycobacterium tuberculosis 的豚鼠，Ditophal（100–200 mg/kg；口服；每日2次；连续4周）可延长平均存活时间，其中100 mg/kg组平均存活时间最长，为35.0天。
别名	Etisul

化学信息

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Ditophal