规格

价格

库存

数量

1 mg

¥ 497

现货

5 mg

¥ 1,230

现货

10 mg

¥ 1,980

现货

25 mg

¥ 3,580

现货

50 mg

¥ 5,130

现货

1 mL x 10 mM (in DMSO)

¥ 1,360

现货

生物活性

产品描述	Butin, the major bioactive flavonoid isolated from Dalbergia odorifera heartwood, possesses oral activity with notable antioxidant, antiplatelet, and anti-inflammatory effects. This compound effectively alleviates myocardial infarction, improves cardiac function, and prevents diabetes-induced cardiac oxidative damage in rats.
体外活性	方法：Butin（12.5，25，50 μM，6小时）处理H9c2，MTT法检测细胞活力，WB检测目标蛋白的表达情况，实时qPCR检测目标基因的表达情况。结果：Butin以剂量依赖性方式提高细胞存活率，增加GSH-px、GSH、SOD、CAT和HO-1的表达，并且以剂量依赖性方式增加细胞质和细胞核中Nrf2水平，增强GSH-px、GSH、SOD、CAT和HO-1的表达。[1]
体内活性	Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rats [1].

化学信息

分子量	272.25
分子式	C₁₅H₁₂O₅
CAS No.	21913-99-5
Smiles	O=C1C2=CC=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)C1
密度	1.485 g/cm3 (Predicted)

储存&溶解度

存储

keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80 mg/mL (293.85 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (12.12 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6731 mL	18.3655 mL	36.7309 mL	183.6547 mL
5 mM	0.7346 mL	3.6731 mL	7.3462 mL	36.7309 mL
10 mM	0.3673 mL	1.8365 mL	3.6731 mL	18.3655 mL
20 mM	0.1837 mL	0.9183 mL	1.8365 mL	9.1827 mL
50 mM	0.0735 mL	0.3673 mL	0.7346 mL	3.6731 mL
100 mM	0.0367 mL	0.1837 mL	0.3673 mL	1.8365 mL