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Apoptosisinducer 18 是一种高效的凋亡诱导剂,对乳腺癌细胞系 MCF-7 表现出显著细胞毒性 (IC50=0.559 μM)。通过与 DNA 结合并引发损伤,同时与 CDK-2 的活性位点结合,以影响其激酶活性,Apoptosisinducer 18 抑制细胞周期进展并促进凋亡。此化合物可用于抗乳腺癌研究。
Apoptosisinducer 18 是一种高效的凋亡诱导剂,对乳腺癌细胞系 MCF-7 表现出显著细胞毒性 (IC50=0.559 μM)。通过与 DNA 结合并引发损伤,同时与 CDK-2 的活性位点结合,以影响其激酶活性,Apoptosisinducer 18 抑制细胞周期进展并促进凋亡。此化合物可用于抗乳腺癌研究。

Apoptosis inducer 18 相关产品
| 产品描述 | Apoptosisinducer 18 is an effective apoptosis-inducing agent that exhibits significant cytotoxicity against the breast cancer cell line MCF-7 (IC50 = 0.559 μM). It induces apoptosis by binding to DNA and causing damage, as well as interacting with the active site of CDK-2, which disrupts kinase activity, thereby impeding cell cycle progression. This compound can be utilized in breast cancer research. |
| 分子式 | C8H12N6O3S |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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