3-Methoxysalicylaldehyde

Name: 3-Methoxysalicylaldehyde
Brand: TargetMol
SKU: TN6748
Rating: 4.5 (1 reviews)

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很棒

纯度: 99.59%

货号 TN6748Cas号 148-53-8

别名 邻香草醛

3-Methoxysalicylaldehyde 是一种天然产物。

3-Methoxysalicylaldehyde

一键复制产品信息

很棒

纯度: 99.59%

货号 TN6748 别名 邻香草醛Cas号 148-53-8

3-Methoxysalicylaldehyde 是一种天然产物。

规格	价格	库存	数量
10 g	¥ 99	待询
1 mL x 10 mM (in DMSO)	¥ 99	现货

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纯度: 99.59%

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产品介绍

3-Methoxysalicylaldehyde AI Summary

3-Methoxysalicylaldehyde exhibits variable partition coefficients (logP) across different solvents, with higher values in chloroform (2.3) and benzene (1.87), suggesting a preference for non-polar environments. It shows bioactivity in various assays, including inhibition of IRE-1α enzyme (IC50 values of 2370.0 nM and 5750.0 nM) and synthetic amyloid beta-42 fibrillation, where it demonstrates 89.0% inhibition and an IC50 value of 6150.0 nM for amyloid beta-42 oligomerization. Additionally, 3-Methoxysalicylaldehyde protects against venom-induced mortality and hemorrhage in Swiss albino mice and displays antiviral activity against SARS-CoV-2 by inhibiting the virus-induced cytotoxicity of VERO-6 cells at a concentration of 10 µM, although its IC50 value exceeds 20000.0 nM. This compound's bioactivities, influenced by its partitioning behavior, suggest potential as a therapeutic agent for conditions such as amyloid beta aggregation, IRE-1α related cellular processes, venom exposure, and viral infections..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	3-Methoxysalicylaldehyde is a natural product.
别名	邻香草醛

化学信息

分子量	152.15
分子式	C₈H₈O₃
CAS No.	148-53-8
Smiles	COC1=CC=CC(C=O)=C1O
密度	1.2143 g/cm3 (Estimated)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (394.35 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5725 mL	32.8623 mL	65.7246 mL	328.6231 mL
5 mM	1.3145 mL	6.5725 mL	13.1449 mL	65.7246 mL
10 mM	0.6572 mL	3.2862 mL	6.5725 mL	32.8623 mL
20 mM	0.3286 mL	1.6431 mL	3.2862 mL	16.4312 mL
50 mM	0.1314 mL	0.6572 mL	1.3145 mL	6.5725 mL
100 mM	0.0657 mL	0.3286 mL	0.6572 mL	3.2862 mL