valsartan

Sacubitril Valsartan (LCZ696)，以1:1摩尔比由Valsartan（一种ARB）和Sacubitril（AHU377）组成，为创新口服血管紧张素受体-脑啡肽酶（ARN）双重抑制剂，旨在治疗高血压与心力衰竭。其作用机制包括抑制炎症、氧化应激及细胞凋亡，有助于改善糖尿病心肌病。

Valsartan (CGP 48933) 是一种血管紧张素 II 受体拮抗剂，有用于高血压和心力衰竭的研究潜力。

Valsartan Ethyl Ester is an impurity of Valsartan, an angiotensin II receptor antagonist used for the treatment of high blood pressure and heart failure.

Valsartan benzyl ester is a intermediate of Valsartan.

4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.

Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan. It is a degradation product formed under acidic conditions.

Valsartan acid, a byproduct of the angiotensin II type 1 (AT1) receptor antagonist Valsartan, emerges through the activated sludge treatment process and has been identified as a contaminant in drinking water.

Valsartan Methyl Ester 是一种强效血管紧张素II 受体拮抗剂，IC50=0.06uM。

Valsartan D9 is a deuterium-labeled valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure.

rac-Valsartan-d9 是 rac-Valsartan 的氘代化合物。rac-Valsartan 的 CAS 号为 137862-53-4。Valsarta 是一种血管紧张素 II 受体拮抗剂，有用于高血压和心力衰竭的研究潜力。

Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。

2R,4R-Sacubitril is an impurity of Sacubitril, which is used in combination with valsartan for the treatment of patients with heart failure.

2S,4R-Sacubitril is an impurity of Sacubitril, which is used in combination with valsartan [for the treatment of patients with heart failure].

(Z)2S,4R-Sacubitril is an impurity of Sacubitril, a compound used in combination with valsartan for treating patients with heart failure.

Losartan potassium impurity E is a compound of Valsartan impurity.

Tandospirone (SM-3997) 是一种具有选择性和高效性的 5-HT1A 受体部分激动剂,具有抗焦虑和抗抑郁活性，增强缬沙坦对自发性高血压大鼠的抗心肌纤维化作用，可用于研究中枢神经系统疾病。