tpp 2

TPP2a is a mitochondrial thioredoxin reductase (TrxR) inhibitor.

NPA101.3 is a a Second-Generation RET VEGFR2 Inhibitor. It is a potential clinical candidate for RET-driven cancers.

Butabindide (UCL-1397) 是三肽肽酶II (TPP II)的选择性抑制剂，对 TPP I 和TPP II 的Ki 值分别为 10 μM 和 7 nM。Butabindide 抑制 TPP II 以保护 CCK-8 免于失活。