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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CRYAB Monoclonal Antibody (7Y406)

Synonyms: HSPB5, CTPP2, CRYAB, CRYA2
货号 TMAT-0656 一键复制产品信息
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Anti-CRYAB Monoclonal Antibody (7Y406) 是一种 Mouse 抗体，靶向 CRYAB。Anti-CRYAB Monoclonal Antibody (7Y406) 可用于 IHC。

Anti-CRYAB Monoclonal Antibody (7Y406)

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Rating icon 还可以
货号 TMAT-0656

别名 HSPB5, CTPP2, CRYAB, CRYA2

Anti-CRYAB Monoclonal Antibody (7Y406) 是一种 Mouse 抗体，靶向 CRYAB。Anti-CRYAB Monoclonal Antibody (7Y406) 可用于 IHC。

Anti-CRYAB Monoclonal Antibody (7Y406)
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产品介绍

生物活性
产品描述
Anti-CRYAB Monoclonal Antibody (7Y406) is a Mouse antibody targeting CRYAB. Anti-CRYAB Monoclonal Antibody (7Y406) can be used in IHC.
别名
HSPB5, CTPP2, CRYAB, CRYA2
Ig Type
IgG2a
克隆号
7Y406
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景Crystallin, alpha B. Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of CRYAB (aa1-175) expressed in E. Coli.
抗原种属
Human
基因名称
CRYAB
基因ID
1410
蛋白名称
Alpha-crystallin B chain
Uniprot ID
P02511
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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