Apricoxib, also known as Benzenesulfonamide 42(4ethoxyphenyl)4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.
Acetaminotadalafil (Standard) is the standard substance of Acetaminotadalafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Acetaminotadalafil is a new analogue of Tadalafil used for the treatment of erectile dysfunction. It acts as a phosphodiesterase 5 inhibitor.