spermidine

Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) 属于天然多胺，存在于核糖体和活组织中，在生物体内具有各种代谢功能。Spermidine 具有炎症减轻、调节脂质代谢、调节细胞生长和死亡的功能。

Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride) 能够维持细胞膜稳定性，提高抗氧化酶特性，改善光系统 II (PSII) 以及相关基因表达，也能够显著抑制 H2O2和 O2.-含量。

DNA-spermidine influences the activity of restricted endonuclease from several bacterial species.

Tris(dihydrocaffeoyl)spermidine为活性化合物，从马铃薯(Solanum tuberosum)块茎中分离得到，主要用于代谢研究。

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine为源自Lycium ruthenicum Murr.的天然化合物，可通过分离提取得到。

Tricoumaroyl spermidine(N1,N5,N10-(Z)-tri-p-coumaroylspermidine) 被发现是一种独特的茶(Camellia sinensis) 花代谢物。

Spermidine-d6 是 2H 标记的 Spermidine。Spermidine 是一种存在于核糖体和活组织中的天然多胺，具有炎症减轻、调节脂质代谢、调节细胞生长和死亡的功能。

N1,N10-Bis(p-coumaroyl)spermidine 对α-葡萄糖苷酶有抑制作用，可从苜蓿的草本植物中提取。

N8-Acetylspermidine dihydrochloride 是一种多胺物质。

N1-Acetylspermidine hydrochloride 是亚精胺的乙酰基衍生物。 N1-Acetylspermidine hydrochloride 是多胺氧化酶的底物，可选择性地提高其在人结直肠腺癌中的水平。

N1,N8-Diacetylspermidine hydrochloride is a polyamines in the human urine.

N1,N8-Diacetylspermidine 是人尿中的一种多胺。N1,N8-Diacetylspermidine 可用作癌症和恶性肿瘤的标记物。

Atherospermidine is a smooth muscle relaxant aporphines from Artabotrys maingayi.

Glutathionylspermidine 是一种多肽，也是大肠杆菌代谢物。

N1,N5,N10-(E)-tri-p-coumaroylspermidine shows free radical-scavenging activity.

Safflospermidine A is a potential natural tyrosinase inhibitor,it shows high antityrosinase activity (IC50 of 13.8 μM).

Safflospermidine B is a potential natural tyrosinase inhibitor, it shows high antityrosinase activity (IC50 of 31.8μM).

Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) 可有效诱导 SSAT (亚精胺 精胺N1-乙酰转移酶) mRNA，并有效稳定 SSAT 酶活性。

Spermine (Neuridine) 作为一个直接的自由基清除剂，具有抗病毒作用，能够保护 DNA 免受自由基的攻击。

OES2-0017 与多胺强协同作用并在低微摩尔范围内表现出生长抑制效果。在低浓度时，该化合物能够抑制精胺 亚精胺乙酰转移酶 (SpeG) (IC50: 34.82 μM) 及其他多胺解毒酶，而在高浓度下则能干扰细菌膜的稳定性。

Jam 2-263 is a spermidine-based catechol ferric carrier - carbocephalosporin.

N1,N11-Diethylnorspermine (DENSPM) 是一种有效的抗癌剂。N1,N11-Diethylnorspermine 是一种精胺类似物,可激活多胺分解代谢。N1,N11-Diethylnorspermine 诱导细胞色素 c 从线粒体中释放，导致 caspase 3的激活。N1,N11-Diethylnorspermine 通过诱导亚精胺 精胺 N1- 乙酰转移酶 (SSAT) 结合产生过氧化氢杀灭多形胶质母细胞瘤 (GBM) 细胞。

Ro 04-5595 is a selective antagonist of NMDA receptors NR2B subunits. Ro 04-5595 had an EC 50 of 186 ± 32 nmol L. Ro 04-5595 was predicted to bind the EVT-101 binding site, not the ifenprodil-binding site. Specific binding, defined with a new NR2B-specific antagonist Ro 04-5595 at 10 microM was fully inhibited by several compounds with the following rank order of affinities--Ro 25-6981 > CP-101,606 > Ro 04-5595 = ifenprodil >> eliprodil > haloperidol > spermine > spermidine > MgCl2 > CaCl2--and partially inhibited by competitive glutamate recognition site antagonists. Complementary high-resolution autoradiographic images using [3H]Ro04-5595 demonstrated strong binding in NR2B receptor-rich regions and low binding in cerebellum where NR2B concentration is low.

Diethylnorspermine, also known as DENSPM, BE-333, DE-333 and N(1),N(11)-Diethylnorspermine, is a highly potent known inducer of the polyamine catabolic enzyme, spermidine spermine N1-acetyltransferase (SSAT). A designed polyamines (PAs) analog which induces cell cycle arrest, inhibits proliferation and induces apoptosis in melanoma, breast, prostate, lung and colon cancer cells..