roxatidine acetate hydrochloride

Roxatidine Acetate hydrochloride (HOE 760) 是一种特异性和竞争性的组胺 H2 受体拮抗剂，能抑制胃酸分泌，可用于胃溃疡和十二指肠溃疡的研究。

Roxatidine hydrochloride is an anti-ulcer agent and histamine antagonist that suppresses gastric acid secretion. It effectively heals duodenal and gastric ulcers and reduces ulcer pain. Roxatidine acetate has an improved safety profile compared to other similar drugs, in part because lower doses of roxatidine acetate are therapeutically effective.

Roxatidine 是 Roxatidine acetate 的活性代谢产物，是组胺 H2受体拮抗剂。Roxatidine 是抗溃疡药，抑制组胺释放（从而抑制质子分泌）并抑制炎症和血管生成的重要标志物 VEGF-1 的产生。具有抗过敏性炎症作用。