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抑制剂&激动剂
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TargetMol产品目录中 "rc 18"的结果
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TargetMol产品目录中 "

rc 18

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  • 抑制剂&激动剂
    5
    TargetMol | Inhibitors_Agonists
  • 抗体抑制剂
    1
    TargetMol | Inhibitory_Antibodies
  • Telitacicept
    RC18
    T783092136630-26-5
    Telitacicept (RC18) 是一种全人源TACI-Fc融合蛋白,兼具BLyS和APRIL抑制作用,有效阻断B淋巴细胞增殖,适用于B细胞自身免疫性疾病研究。
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  • Corrector C18
    Corrector C-18, Corrector C 18
    T31013
    Corrector C18 is a class I mutation corrector which rescues CFTR mutations in nucleotide-binding domain 1 (NBD1) by modulating proteostasis.
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  • ARC186
    T75106
    ARC 186 是一种核酸适配体,是高效的补体抑制剂,通过阻断转化酶催化的C5 激活发挥作用。
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  • NH2-C6-ARC186
    T78191
    NH2-C6-ARC186是带有NH2-C6接头的ARC186衍生物,可用于与其他肽或分子偶联。它作为一种适体,是一种高效的补体抑制剂,通过抑制转化酶催化的C5活化发挥作用。
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  • Neuromedin C (trifluoroacetate salt)
    T35669
    Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulation in mice when administered intradermally at doses ranging from 1 to 300 nmol site, which is inhibited by the BB2 bombesin receptor agonist RC-3095 and reduced in mast cell-deficient mice. Neuromedin C (3.2 nmol kg, i.p.) reduces rat glucose consumption by approximately 50% for up to one hour.
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