rat and human tspo

ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. ONO-2952 is a potent and selective translocator protein 18 kDa (TSPO) antagonist (Ki: 0.33-9.30 nM for rat and human TSPO). ONO-2952 has the potential for i

(R)-ONO-2952 是 ONO-2952 的 R 型异构体。ONO-2952 是选择性的，口服有效的 TSPO 拮抗剂，抑制大鼠和人 TSPO 的 Kis 为 0.330-9.30 nM。