pz-1

Pz-1 是 VEGFR2 和 RET 酪氨酸激酶的抑制剂，可阻断 RET 刺激生长所需的血液供应。

PZ-1922（Compound 16），是能穿透大脑屏障的5-HT6R 5-HT3R拮抗剂，其Ki值分别为17 nM和0.45 nM。该化合物还能可逆地抑制MAO-B（pIC50：8.93）。在大鼠的新物体识别(NOR)测试中，PZ-1922逆转了Scopolamine (SCOP)诱导的记忆缺陷；同样，在T迷宫测试中，它防止了Aβ诱发的记忆衰退。

PZ-1190是一种多靶点配体，针对啮齿动物的serotonin和dopamine受体，展现出潜在的抗精神病活性。

PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.

PZ15527是一种靶向Bcl-xl的PROTAC。

PPZ1 is a novel DAG-activated TRPC3 TRPC6 TRPC7 channels activator.

Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis (MIC = 20 μM) but not S. aureus, E. coli, or B. cereus (MICs = >20 μM). It is cytotoxic to HL-60 promyelocytic leukemia cells (IC50 = 56.61 μM) but not THP-1 acute monocytic leukemia or PC3 prostate cancer cells (IC50s = >80 μM).