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TargetMol产品目录中 "protac k ras degrader 1"的结果
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TargetMol产品目录中 "

protac k ras degrader 1

"的结果
  • 抑制剂&激动剂
    12
    TargetMol | Inhibitors_Agonists
  • PROTAC
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    TargetMol | PROTAC
  • PROTAC K-Ras Degrader-1
    T138442378258-52-5
    PROTAC K-Ras Degrader-1 是一种基于 Cereblon E3 配体的 PROTAC 降解剂,可降解 K-Ras
    • ¥ 5480
    待询
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    数量
  • K-Ras ligand-Linker Conjugate 1
    T18054
    K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
    • 待询
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  • K-Ras ligand-Linker Conjugate 2
    T18055
    K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC K-Ras Degrader-1, which is a highly effective PROTAC K-Ras degrader with a degradation efficacy of ≥70% in SW1573 cells[1].
    • 待询
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    数量
  • K-Ras ligand-Linker Conjugate 3
    T180562378261-87-9
    K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). This compound is essential in the synthesis of PROTAC K-Ras Degrader-1, a potent PROTAC K-Ras degrader that demonstrates a degradation efficacy of ≥70% in SW1573 cells[1].
    • 待询
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    数量
  • K-Ras ligand-Linker Conjugate 4
    T180572378261-83-5
    K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The compound has the potential to be used in the synthesis of PROTAC K-Ras Degrader-1, a powerful degrader of K-Ras that has been shown to exhibit a degradation efficacy of ≥70% in SW1573 cells[1].
    • ¥ 927
    5日内发货
    规格
    数量
  • K-Ras ligand-Linker Conjugate 5
    T180582378261-85-7
    K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The K-Ras ligand-Linker Conjugate 5 plays a crucial role in the synthesis of PROTAC K-Ras Degrader-1, a highly potent K-Ras degrader. In SW1573 cells, this degrader exhibits an impressive degradation efficacy of ≥70% [1].
    • ¥ 1060
    5日内发货
    规格
    数量
  • K-Ras ligand-Linker Conjugate 6
    T180592378261-89-1
    K-Ras ligand-Linker Conjugate 6 是一种结合 K-Ras 招募片段配体和PROTAC连接子的化合物,可募集 E3 连接酶,合成 PROTAC K-Ras Degrader-1.
    • ¥ 695
    In stock
    规格
    数量
  • THP-PEG4-Pyrrolidine(N-Boc)-CH2OH
    T188462378261-80-2
    THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a polyethylene glycol (PEG) based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTAC K-Ras Degrader-1, as documented in reference [1].
    • ¥ 270
    5日内发货
    规格
    数量
  • THP-PEG4-Pyrrolidine(N-Me)-CH2OH
    T188472378261-81-3
    THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1].
    • ¥ 387
    5日内发货
    规格
    数量
  • Tos-PEG4-THP
    T1885386259-89-4
    Tos-PEG4-THP is a polyethylene glycol (PEG) derivative utilized as a linker in the synthesis of PROTAC K-Ras Degrader-1, a potential therapeutic compound for targeted degradation of K-Ras protein [1].
    • ¥ 1353
    5日内发货
    规格
    数量
  • PROTAC K-Ras Degrader-3
    T2005213043670-68-1
    PROTAC K-Ras Degrader-3(化合物 40)为特定靶向K-RasPROTAC降解剂,其在SW620 KRAS G12D 细胞上体现出极高效力,DC50 值不超过1 nM,同时对SW620 3D 细胞生长的GI50 值亦不高于10 nM。该化合物常用于癌症领域的研究工作。
    • 待询
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  • PROTAC KRAS G12C degrader-2
    T872662378257-72-6
    PROTACKRAS G12C degrader-2 (compound 432) 作为一种双功能化合物,主要功能是调节K-Ras蛋白的水解。该化合物一端配备了小脑细胞凋亡蛋白抑制剂 (IAP),而另一端则含有能够与KRAS结合的片段。
    • 待询
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