picolinamide

Picolinamide (Picolinoylamide) 被发现是大鼠胰岛细胞核聚 (ADP-核糖) 合成酶的强抑制剂。

N-Methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67100。

N-(2-Hydroxyphenyl)picolinamide是一种用于生化反应研究的活性分子。

Picolinamidoxime is a biochemical substance.

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide 是芳香谜，是是抗肿瘤药物瑞非尼的代谢产物。

4-Bromo-N-methylpicolinamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64454，CAS号为 1209459-88-0。

4-(4-Formamidophenoxy)-N-methylpicolinamide 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64459。

4,6-Dichloro-N-methylpicolinamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64568，CAS号为 1379324-09-0。

4-Chloro-N-methylpicolinamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66513，CAS号为 220000-87-3。

4-Chloro-N,N-dimethylpicolinamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67664，CAS号为 114780-06-2。

Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution profiles, and robust in vivo stability.

Melanoma is a lethal skin cancer. The early detection of melanoma using positron emission tomography (PET) probes is critical for improving the survival of melanoma patients. Melanin probe-2 is a non-radioactive bromo-picolinamide precursor that has been used for the synthesis of18F-picolinamides based PET probe (melanin probe-1). The tumor-targeting efficacy and imaging property of three melanin probes were evaluated in B16F10 tumor-bearing mice.18F-1 and18F-3 had much lower tumor uptake compared with18F-2 (Melanin probe-2), which were 12.74 ± 1.70, 16.61 ± 2.60, and 16.87 ± 1.23 %ID g at 0.5, 1, and 2 h, respectively[1].