pal 4

PAL-4刺激 LYPLAL1 的活性, 一种特征不佳的丝氨酸水解酶，与人类代谢特征具有复杂的遗传联系。

Fmoc-D-4-Pal-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65478，CAS号为 205528-30-9。

Fmoc-4-Pal-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65484，CAS号为 169555-95-7。

H-D-4-Pal-OH.2HCl 是一种氨基酸衍生物，在生命科学相关研究中具有广泛的应用。

P4pal10为PAR4拮抗剂，能在体内抑制凝血酶介导的小鼠血小板聚集，并显著减少Carrageenan引起的水肿及粒细胞浸润。

P4pal10 TFA 是 P4pal10 的三氟乙酸(TFA) 盐状态.作为蛋白酶激活受体 4 (PAR4) 的拮抗剂,它能有效地抑制血小板的聚集以及组织因子 (TF) 诱导的凝血酶生成,展示出显著的抗凝和抗血栓效果.此外,P4pal10 TFA 在减轻 Carrageenan 诱发的水肿和粒细胞浸润方面表现出良好的活性,并能改善大鼠心肌缺血 再灌注 (I R) 模型中的组织损伤.

Matrixyl Acetate(214047-00-4 free base) (Palmitoyl pentapeptide) 是一种用于抗皱化妆品的 matrikine。

Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when used at concentrations of 0.002, 0.004, and 0.008 wt%.2 Following topical administration, pal-KTTKS (50 μg/cm2) is found in the stratum corneum, epidermis, and dermis of isolated hairless mouse skin.1 It can self-assemble into flat tapes and extended fibrillar structures.3 Pal-KTTKS has been detected in anti-wrinkle creams.4 |1. Choi, Y.L., Park, E.J., Kim, E., et al. Dermal stability and in vitro skin permeation of collagen pentapeptides (KTTKS and palmitoyl-KTTKS). Biomol. Ther. (Seoul) 22(4), 321-327 (2014).|2. Jones, R.R., Castelletto, V., Connon, C.J., et al. Collagen stimulating effect of peptide amphiphile C16-KTTKS on human fibroblasts. Mol. Pharm. 10(3), 1063-1069 (2013).|3. Castelletto, V., Hamley, I.W., Whitehouse, C., et al. Self-assembly of palmitoyl lipopeptides used in skin care products. Langmuir 29(29), 9149-9155 (2013).|4. Chirita, R.-I., Chaimbbault, P., Archambault, J.-C., et al. Development of a LC-MS/MS method to monitor palmitoyl peptides content in anti-wrinkle cosmetics. Anal. Chim. Acta 641(1-2), 95-100 (2009).

Ac-PAL-AMC is a fluorogenic substrate for the β1i LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β1i LMP2 subunit of the 20S immunoproteasome. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation emission maxima of 351 430 nm, respectively.

Fmoc-D-3-Pal-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65472，CAS号为 142994-45-4。