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抑制剂&激动剂
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  • 抑制剂&激动剂
    10
    TargetMol | Inhibitors_Agonists
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  • GJ071 oxalate
    GJ 071, GJ-071, GJ071
    T319321216676-34-4In house
    GJ071 oxalate 是一种无义抑制剂。无义抑制剂(NonSups)诱导“读出”,即在提前终止密码子处选择近同源tRNA,并将相应的氨基酸插入新生多肽中。
    • ¥ 463
    In stock
    规格
    数量
  • Ataluren
    PTC124
    T1805775304-57-9
    Ataluren (PTC124) 是一种可口服的 CFTR-G542X 无义等位基因抑制剂。
    • ¥ 255
    In stock
    规格
    数量
  • eIF4A3-IN-1
    T111702095486-67-0
    eIF4A3-IN-1 是一种具有选择性和高效性的真核起始因子 4A3 (eIF4A3) 抑制剂,IC50 值为 0.26 μM。eIF4A3-IN-1 在高浓度时抑制细胞无义介导的 RNA 衰变。
    • ¥ 1780
    In stock
    规格
    数量
  • NMDI14
    T12235307519-88-6
    NMDI14 是无义介导的 RNA 衰变抑制剂。
    • ¥ 255
    In stock
    规格
    数量
  • ELX-02 disulfate
    NB-124 disulfate
    T193062244622-33-9
    ELX-02 disulfate (also referred to as NB-124 disulfate) is a synthetic eukaryotic ribosome selective glycoside (ERSG). This compound is currently in development as a therapy specifically designed to address genetic diseases resulting from nonsense mutations.
    • ¥ 29980
    4-6周
    规格
    数量
  • ELX-02 sulfate
    NB-124 sulfate
    T193071375073-94-1
    ELX-02 sulfate, also known as NB-124 sulfate, is a novel compound currently under development as a therapeutic agent for genetic diseases triggered by nonsense mutations. This investigational compound, an advanced synthetic eukaryotic ribosome selective glycoside (ERSG), shows promising potential for targeted treatment.
    • 待询
    3-6月
    规格
    数量
  • Clitocine
    克力托辛
    T30969105798-74-1
    Clitocine 是一种来从蘑菇中提取的一种腺苷类似物,是一种有效的转录通读剂,是一种无义突变的抑制剂,具有抗癌活性,可诱导携带 p53 无义突变等位基因的细胞产生 p53 蛋白。Clitocine 通过促进 Mcl-1 降解来增强 TRAIL 介导的人结肠癌细胞凋亡。
    • ¥ 1480
    In stock
    规格
    数量
  • ELX-02
    NB-124,NB 124,NB124,ELX02,ELX 02
    T316161375073-95-2
    ELX-02, also known as NB-124, is a eukaryotic ribosomal selective glycoside (ERSG) designed to increase the read-through activity in patients with nonsense mutations and enable the production of sufficient amounts of full-length functional protein to rest
    • 待询
    规格
    数量
  • GJ072
    GJ-072, GJ 072
    T31933943092-47-5
    GJ-072 is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into nascent polypeptide.
    • 待询
    规格
    数量
  • DMNB-caged-Serine
    T40889780009-55-4
    DMNB-caged-Serine is a photocaged amino acid . DMNB is a caging group which is sensitive to blue light. DMNB-caged-Serine can be incorporated into proteins in Saccharomyces cerevisiae in response to the amber nonsense codon TAG, which can be helpful for controlling the chemical composition of mammalian proteins..
    • ¥ 643
    5日内发货
    规格
    数量
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