|
TMPY-04730
|
LAG-3 Protein, Human, Recombinant (His)
LAG-3,lymphocyte-activation gene 3,CD223
|
Human
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-04939
|
LAG-3 Protein, Human, Recombinant
LAG-3,lymphocyte-activation gene 3,CD223
|
Human
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-05092
|
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
lymphocyte-activation gene 3
|
Cynomolgus
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-05568
|
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
BCMA,TNFRSF13A,tumor necrosis factor receptor superfamily me...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-05319
|
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
BCMA,TNFRSF13A,CD269,tumor necrosis factor receptor superfam...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-04493
|
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)
tumor necrosis factor receptor superfamily member 17,BCMA,CD...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-03213
|
BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)
tumor necrosis factor receptor superfamily member 17
|
Rhesus
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-01257
|
uPAR/PLAUR Protein, Mouse, Recombinant (His)
uPAR,Cd87,u-PAR,plasminogen activator, urokinase receptor
|
Mouse
|
HEK293
|
|
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and uPA levels in both resected tumor tissue and plasma are of independent prognostic significance for patient survival in several types of human cancer. This system has classically been thought to drive tumor progression by mediating directed extracellular proteolysis on the surface... |
|
TMPY-02141
|
uPAR/PLAUR Protein, Human, Recombinant (His)
UPAR,CD87,plasminogen activator, urokinase receptor,U-PAR,UR...
|
Human
|
HEK293
|
|
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and uPA levels in both resected tumor tissue and plasma are of independent prognostic significance for patient survival in several types of human cancer. This system has classically been thought to drive tumor progression by mediating directed extracellular proteolysis on the surface... |
|
TMPJ-00331
|
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
IFN-al,CRF2-1,IFN-alpha/beta receptor 1,human interferon-α r...
|
Rhesus macaque
|
Human Cells
|
|
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory... |
|
TMPK-01035
|
SP17 Protein, Mouse, Recombinant (His)
SPA17,Sperm protein 17,CT22,Sp17-1
|
Mouse
|
E. coli
|
|
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. |
|
TMPK-00357
|
CD229 Protein, Human, Recombinant (His & Avi)
LY9,T100,AI893573,SLAMF3,Lgp100,CD229
|
Human
|
HEK293
|
|
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. |
|
TMPK-00974
|
SP17 Protein, Human, Recombinant (His)
Sperm protein 17,SPA17,CT22,Sp17-1
|
Human
|
E. coli
|
|
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. |
|
TMPK-00358
|
CD229 Protein, Human, Recombinant (His & Avi), Biotinylated
T100,Lgp100,LY9,AI893573,CD229,SLAMF3
|
Human
|
HEK293
|
|
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. |
|
TMPY-04409
|
GRK6 Protein, Human, Recombinant (His & GST)
G protein-coupled receptor kinase 6,GPRK6
|
Human
|
Baculovirus-Insect Cells
|
|
G protein-coupled receptor kinase 6, also known as G protein-coupled receptor kinase GRK6, GRK6, and GPRK6, is a lipid-anchor protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRK6 / GPRK6 contains one AGC-kinase C-terminal domain, one protein kinase domain, and one RGS domain. This protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding differen... |
|
TMPK-01193
|
GPRC5D Protein-VLP, Mouse, Recombinant
MGC129713,orphan G-protein coupled receptor,GPRC5D,MGC129714
|
Mouse
|
HEK293
|
|
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
|
TMPK-00528
|
GPRC5D Protein-VLP, Cynomolgus, Recombinant
MGC129713,GPRC5D,MGC129714,orphan G-protein coupled receptor
|
Cynomolgus
|
HEK293
|
|
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
|
TMPY-02924
|
RGS1 Protein, Human, Recombinant (His)
1R20,IER1,BL34,HEL-S-87,regulator of G-protein signaling 1,I...
|
Human
|
E. coli
|
|
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization of T and B cells in lymphoid organs. RGS1 expression may be a prognostic marker for risk stratification and a promising target for the development of a new Multiple myeloma (MM) therapy. The markers in the RGS1 gene might be in linkage disequilibrium with a protective allele that ... |
|
TMPY-06719
|
GPRC5D Protein, Human, Recombinant (His & FLAG)
GPRC5D
|
Human
|
HEK293
|
|
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target... |
|
TMPY-06601
|
GPRC5D Protein, Human, Recombinant, Biotinylated
GPRC5D
|
Human
|
HEK293
|
|
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target... |
|
TMPY-06806
|
GPRC5D Protein, Human, Recombinant, Fluorescent
GPRC5D
|
Human
|
HEK293
|
|
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target... |
|
TMPY-06718
|
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent
GPRC5D
|
Human
|
HEK293
|
|
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target... |
|
TMPY-06494
|
GPRC5D Protein-VLP, Human, Recombinant
GPRC5D
|
Human
|
HEK293
|
|
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target... |
|
TMPY-06807
|
GPRC5D Protein, Mouse, Recombinant (Flag)
|
Mouse
|
HEK293
|
|
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target... |
|
TMPJ-00291
|
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
IL-6R-α,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Int...
|
Human
|
Human Cells
|
|
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an... |
|
TMPY-05746
|
LAG-3 Protein, Mouse, Recombinant
lymphocyte-activation gene 3,LAG-3,Ly66,CD223
|
Mouse
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-04612
|
LAG-3 Protein, Mouse, Recombinant (His)
LAG-3,Ly66,lymphocyte-activation gene 3,CD223
|
Mouse
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-04731
|
LAG-3 Protein, Human, Recombinant (mFc)
lymphocyte-activation gene 3,CD223,LAG-3
|
Human
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-06931
|
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
lymphocyte-activation gene 3,CD223,LAG-3
|
Human
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-03759
|
LAG-3 Protein, Rat, Recombinant (His)
lymphocyte-activation gene 3
|
Rat
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-04611
|
LAG-3 Protein, Mouse, Recombinant (hFc)
lymphocyte-activation gene 3,Ly66,LAG-3,CD223
|
Mouse
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-05130
|
LAG-3 Protein, Human, Recombinant, Biotinylated
lymphocyte-activation gene 3,CD223,LAG-3
|
Human
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPY-04528
|
LAG-3 Protein, Human, Recombinant (hFc)
lymphocyte-activation gene 3,CD223,LAG-3
|
Human
|
HEK293
|
|
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, L... |
|
TMPJ-00130
|
SLAMF2 Protein, Human, Recombinant (hFc & His)
Leukocyte antigen MEM-102,CD48 antigen,CD48,BCM1 surface ant...
|
Human
|
Human Cells
|
|
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cel... |
|
TMPJ-00694
|
BRD4 Protein, Human, Recombinant (His & Flag)
MCAP,HUNK1,HUNKI,bromodomain-containing protein 4
|
Human
|
E. coli
|
|
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure. BRD bromodomains serve as recognition motifs for ... |
|
TMPY-02843
|
GPX7 Protein, Human, Recombinant (hFc)
GSHPx-7,UNQ469/PRO828,NPGPx,CL683,glutathione peroxidase 7,G...
|
Human
|
HEK293
|
|
GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to differ by overlapping exons with different boundaries. GPX7 is an enzyme. It has molecular functions (glutathione peroxidase activity, oxidoreductase activity) and to localize in various compartments (extracellular space, extracellular region). GPX7 gene has been proposed to part... |
|
TMPY-01211
|
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)
BCMA,tumor necrosis factor receptor superfamily member 17,Tn...
|
Mouse
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-05197
|
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
BCMA,TNFRSF13A,tumor necrosis factor receptor superfamily me...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-00966
|
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc)
Tnfrsf13a,BCMA,tumor necrosis factor receptor superfamily me...
|
Mouse
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-05595
|
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
tumor necrosis factor receptor superfamily member 17,BCMA,BC...
|
Mouse
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-06757
|
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD269,TNFRSF13A,BCMA,tumor necrosis factor receptor superfam...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-05567
|
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
tumor necrosis factor receptor superfamily member 17,BCMA,TN...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-02913
|
BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc)
tumor necrosis factor receptor superfamily member 17
|
Rat
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-05385
|
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
CD269,BCM,tumor necrosis factor receptor superfamily member ...
|
Human
|
HEK293
|
|
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
|
TMPY-05328
|
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
CD269,TNFRSF13A,BCM,BCMA,tumor necrosis factor receptor supe...
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Human
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HEK293
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Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
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TMPY-05136
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BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
tumor necrosis factor receptor superfamily member 17
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Rhesus
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HEK293
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Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13BBAFF), and to lead to NF-kappaB and MAPK8/JNK activation. TNFRSF17/... |
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TMPY-01017
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uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc)
plasminogen activator, urokinase receptor,u-PAR,uPAR,Cd87
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Mouse
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HEK293
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Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and uPA levels in both resected tumor tissue and plasma are of independent prognostic significance for patient survival in several types of human cancer. This system has classically been thought to drive tumor progression by mediating directed extracellular proteolysis on the surface... |
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TMPY-01710
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IkB alpha/NFKBIA Protein, Human, Recombinant (His)
IkB α,IKBA,nuclear factor of kappa light polypeptide gene en...
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Human
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E. coli
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Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NFKBIA inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. Also, NFKBIA blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-kB's proper function... |
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TMPH-03208
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IL-6 Protein, Rabbit, Recombinant (His)
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Rabbit
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Yeast
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Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter... |
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TMPH-03500
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IL-6 Protein, Sheep, Recombinant (GST)
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Sheep
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E. coli
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Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter... |
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