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TargetMol产品目录中 "

mmp 25

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  • 抑制剂&激动剂
    6
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    3
    TargetMol | Recombinant_Protein
  • 多肽产品
    1
    TargetMol | Peptide_Products
  • 天然产物
    3
    TargetMol | Natural_Products
  • Shogaol
    [6]-Shogaol, 6-姜烯酚, 6-Shogaol, 姜烯酚
    T6S1699555-66-8
    6-Shogaol (6-Shogaol) 是从生姜中分离的一种天然产物,具有抗癌、抗炎和抗氧化的多种生物活性。
    • ¥ 247
    In stock
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    数量
    TargetMol | Inhibitor Sale
  • Panduratin A
    泛影素 A
    T3387589837-52-5
    Panduratin A(泛影素 A)是一种天然的查尔酮衍生物,在人口腔表皮样癌KB细胞中对MMP-9具有抑制活性;对DENV-2的NS3蛋白酶具有抑制活性(Ki=25 μM);对人雄激素非依赖性前列腺癌细胞PC-3和DU-145有明显的细胞毒性;还能够激活LKB1-AMPK-PPARα δ信号通路,增强肌细胞线粒体的氧化能力。
    • ¥ 1560
    In stock
    规格
    数量
  • FSL-1 TFA
    T35701
    FSL-1 TFA, a bacterial-derived toll-like receptor 2 6 (TLR2 6) agonist, enhances resistance to experimental HSV-2 infection[1]. FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB AP-1 signaling pathways in monocytic THP-1 cells[2]. FSL-1 significantly reduces HSV-2 replication in human vaginal epithelial cells (EC)[1].FSL-1 induces significant resistance to experimental genital HSV-2 infection through elaboration of a specific cytokine response profile[1].FSL-1 (50 ng mL, 24 hours) induces MMP-9 expression at both mRNA and protein levels in human monocytic THP-1 cells[2].FSL-1 activates the MAP kinase NF-κB signaling pathway[2]. Cell Viability Assay[1] Cell Line: V11I, V12I or V19I immortalized human vaginal EC FSL-1 application significantly protectes against genital HSV-2 challenge in mice[1]. Animal Model: Female Swiss-Webster mice (weighing 20-25 g)[1] [1]. William A Rose 2nd, et al. FSL-1, a bacterial-derived toll-like receptor 2 6 agonist, enhances resistance to experimental HSV-2 infection. Virol J. 2009 Nov 10;6:195. [2]. Cathryn J Kurkjian,et al. The Toll-Like Receptor 2 6 Agonist, FSL-1 Lipopeptide, Therapeutically Mitigates Acute Radiation Syndrome. Sci Rep. 2017 Dec 11;7(1):17355.
    • 待询
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  • Aminopeptidase N Inhibitor
    T36943596108-59-7
    Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N CD13 (IC50 = 25 μM). It is selective for AP-N CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM.
    • ¥ 10600
    6-8周
    规格
    数量
  • 25(R,S)-Ruscogenin
    (25RS)鲁斯可皂苷元, (25RS)-Ruscogenin
    T5740874485-32-2
    25(R,S)-Ruscogenin 能够调节 PI3K Akt mTOR 信号通路,抑制 MMP-2、MMP-9、uPA、VEGF 和 HIF-1α 的表达,阻碍肝癌转移。 它能够抑制 TLR4信号通路,减轻 LPS 诱导的肺内皮细胞凋亡。
    • ¥ 445
    In stock
    规格
    数量
  • MMP2-IN-2
    T605511772-39-0
    MMP2-IN-2 是一种具有选择性的 MMP-2 (基质金属蛋白酶)抑制剂,具有潜在的抗癌抗肿瘤活性,抑制 MMP-13、MMP-9 和 MMP-8,可用于研究癌症和免疫疾病。
    • ¥ 329
    In stock
    规格
    数量