m-133

M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.

Pefabloc is an irreversible serine proteinase inhibitor. Pefabloc efficiently inhibits both human and rat platelet activating factor (PAF)-degrading acetylhydrolase (acetylhydrolase).

M133 peptide 是冠状病毒特异性的CD4T细胞表位，具有免疫优势，尤其是在感染嗜神经冠状病毒（小鼠肝炎病毒的JHM株）的小鼠中。M133 peptide 通过与MHC II 分子结合形成MHC/肽复合物，被特异性TCR识别，从而激活CD4T细胞。

UCM-1336 (3,3′-(Octylimino)bis[N-phenylpropanamide]) 是一种有效的 ICMT 抑制剂，IC50 为 2 μM，对参与 Ras 翻译后修饰的其他酶具有选择性。

RM-133 is a promising pro-apoptotic agent which shows activity on various cancer cell lines.

UCM-13369 (Compound 4b) 作为一种NPM1抑制剂，它能特异性地针对 NPM1 C+ 的 C 端 DNA 结合域，并下调其相关信号通路。此外，UCM-13369 还能诱导 AML 细胞系与原代细胞的凋亡，对于AML的研究具有重要用途。

Abacavir hydroxyacetate 是一个具有口服活性的核苷类似物逆转录酶抑制剂.具有抗 HIV 和免疫调节活性，在小鼠模型中诱导动脉血栓形成，可用于研究 HIV 感染。

Hydrocortisone cypionate (Standard) is the standard substance of Hydrocortisone cypionate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid.

Hydrocortisone hemisuccinate (Standard) 是 Hydrocortisone hemisuccinate 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素， 是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性，可用于研究溃疡性结肠炎。

Hydrocortisone valerate (Standard) 是 Hydrocortisone valerate 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Hydrocortisone Valerate (Westcort) 具有抗炎、止痒和血管收缩的特性。

Eugenol (Standard) 是 Eugenol 的标准品。适用于定量分析、质量控制及生化实验等相关研究。Eugenol (Allylguaiacol) 是一种从丁香中发现的精油，抑制脂质的过氧化，具有抗菌，驱虫和抗氧化活性。

Syringaresinol diglucoside (Standard) 是 Syringaresinol diglucoside 的标准品。适用于定量分析、质量控制及生化实验等相关研究。Syringaresinol diglucoside (Syringaresinol-di-O-glucoside) 是一种提取自竹叶中的天然化合物。

Hydroxy Dimetridazole-d3 (Standard) 是 Hydroxy Dimetridazole-d3 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Hydroxy Dimetridazole-d3 是 Hydroxy Dimetridazole 的氘代化合物。Hydroxy Dimetridazole 的 CAS 号为 936-05-0。Hydroxy Dimetridazole 是Dimetridazol的羟基化代谢产物。Dimetridazol 是一种硝基咪唑类药物，可用于对抗原生动物感染。

Hydroxy Ipronidazole-d3 (Standard) 是 Hydroxy Ipronidazole-d3 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Hydroxy Ipronidazole-d3 是 Hydroxy Ipronidazole 的氘代化合物。Hydroxy Ipronidazole 的 CAS 号为 35175-14-5。

Hydroxychlorodenafil (Standard) is the standard substance of Hydroxychlorodenafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Hydroxychlorodenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil.

Hydroxymetronidazole (Standard) is the standard substance of Hydroxymetronidazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Hydroxymetronidazole (Metronidazole-OH) is a nitroimidazole compound that functions as a metabolite of Metronidazole. It is commonly employed in poultry research to investigate bacterial and protozoal diseases, as well as in the study of swine dysentery and genital trichomoniasis in cattle.

Hydroxyphenyllactic acid (Standard) 是 Hydroxyphenyllactic acid 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Hydroxyphenyllactic acid 是具有抗真菌活性的代谢物。

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (FAH) deficiency in mice when administered to pregnant dams.2It exhibits hepatoprotective effects inFAH-/-mice, such as prevention of increases in plasma levels of aspartate serine aminotransferase (AST) and conjugated bilirubin, when administration is continued following birth at a dose of 1 mg/kg. Nitisinone (100 μg) decreases urinary excretion of homogentisate and increases urinary excretion of HPPA, HPLA, and 4-hydroxyphenylacetate in a mouse model of alkaptonuria induced by ethylnitrosourea.3Formulations containing nitisinone have been used in the treatment of hereditary tyrosinemia type 1 (HT-1). 1.Ellis, M.K., Whitfield, A.C., Gowans, L.A., et al.Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dioneToxicol. Appl. Pharmacol.133(1)12-19(1995) 2.Grompe, M., Lindstedt, S., al-Dhalimy, M., et al.Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type INat. Genet.10(4)453-460(1995) 3.Suzuki, Y., Oda, K., Yoshikawa, Y., et al.A novel therapeutic trial of homogentisic aciduria in a murine model of alkaptonuriaJ. Hum. Genet.44(2)79-84(1999)