larvicidal

3-Butylidenephthalide (Butylidene phthalide) 是从 Ligusticum chuanxiongHort 鉴定出的一种邻苯二甲酸酐衍生物，有杀虫活性。

Hexythiazox 是一种螨类生长调节剂和噻唑烷类杀螨剂，对多种螨类具有长效杀虫作用，适用于植物从萌芽到结果的任何生长阶段。

Tectoquinone 具有很强的杀蚊幼虫活性。

Limonin glucoside is a natural product in citrus fruits. It inhibits expression of HIV-1 and HTLV-1 in infected cells, induces apoptosis in colon adenocarcinoma cells, and exhibits larvicidal activity against species of Aedes.

Amorphigenin, a rotenoid compound, exhibits a strong larvicidal activity.

Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 2 μg ml) and has larvicidal activity toward Artemia (LC50 = 1.7 μg ml). Nornidulin has cytotoxic activity in MOLT-3 cells (IC50 = 35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >116.4 μM).

Nidulin is a depsidone originally isolated from A. nidulans. It is active against the bacteria M. tuberculosis and M. ranoe, as well as the fungi T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC = 4 μg ml) and has larvicidal activity toward Artemia (LC50 = 2.8 μg ml). Nidulin is cytotoxic to MOLT-3 cells (IC50 = 21.2 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s = >112.7 μM). It inhibits aromatase with an IC50 value of 11.2 μM.

Suberosin 可分离自Plumbago zeylanica 中，通过调节NF-AT 和NF-κB，抑制PHA-诱导的 PBMC 细胞增殖并捕获细胞周期G1过渡到 S 期，具有抗炎和抗血凝的活性。

5-Pentadecylresorcinol (Adipostatin A) 对埃及伊蚊具有良好的杀幼虫活性，它是甘油3-磷酸脱氢酶 (GPDH) 抑制剂，IC50值为 4.1 μM。

RyRs activator 1 是兰尼碱受体 (RyRs) 的有效激活剂。RyRs activator 1 在 0.5 mg L 时，杀幼虫活性为100%，在 0.01 mg L 时，杀幼虫活性为90%。

RyRs activator 2 是兰尼碱受体 (RyRs) 的有效激活剂。RyRs activator 2 的杀幼虫活性为 30%，与氯虫苯甲酰胺 (30%) 相当，优于氰虫苯甲酰胺 (10%)。

Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物，是PD-L1抑制剂，可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1，有用于癌症免疫的潜力。

dl-Maackiain (Demethylpterocarpin) 是分离自Maackia amurensis Rupr.et Maxim 的一种杀幼虫剂，针对埃及伊蚊，其LD50为 21.95 μg ml。

Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.3 Methazolamide is larvicidal, with a 50% larvicidal concentration (LC50) value of 724 ppm, but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used in the treatment of glaucoma.

RyRs activator 4为一款昆虫兰尼碱受体激活剂，对粘虫幼虫显示出显著的杀灭活性，其半致死浓度(LC50)为1.32 mg L。

GABA-IN-2 (Compound 5) 为GABA抑制剂，展现出杀幼虫效果和显著的杀虫能力，在浓度50 mg L下的死亡率达到87%。

GABA-IN-1 (Compound 6)为GABA抑制剂，具备显著的杀幼虫效能与杀虫功能，在浓度为50 mg L时，致死率达93%。

AChE-IN-70(compound 4)是一种有效的AChE抑制剂,对Culex pipiens L.的蚊子幼虫具有杀灭效果,适用于蚊虫防治的研究.

1-Hydroxy-2-methylanthraquinone exhibits promising larvicidal activity.

Evodol may as an anti-inflammatory agent or lead compound, it shows inhibitory activity on nitric oxide (NO) production in lipopolysaccharide -activated RAW264.7 macrophages. Evodol and limonin possess larvicidal activity against the Asian tiger mosquitoe

6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae.

Alepterolic acid exhibits larvicidal properties against Aedes aegypti (L.) (Diptera, Culicidae), with LC50 of 87.3 ppm.

Burchellin has larvicidal activity, it can interfer with the development cycle of the mosquito, where its strongest toxic effect is 100% mortality in larvae (L3) at concentrations ‰¥ 30 ppm. Burchellin and licarin A have activity against Trypanosoma cruzi

Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice.