Limonin glucoside is a natural product in citrus fruits. It inhibits expression of HIV-1 and HTLV-1 in infected cells, induces apoptosis in colon adenocarcinoma cells, and exhibits larvicidal activity against species of Aedes.
Evodol may as an anti-inflammatory agent or lead compound, it shows inhibitory activity on nitric oxide (NO) production in lipopolysaccharide -activated RAW264.7 macrophages. Evodol and limonin possess larvicidal activity against the Asian tiger mosquitoe
Burchellin has larvicidal activity, it can interfer with the development cycle of the mosquito, where its strongest toxic effect is 100% mortality in larvae (L3) at concentrations ¥ 30 ppm. Burchellin and licarin A have activity against Trypanosoma cruzi
Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice.