kifunensine

Kifunensine, a potent and selective inhibitor of class I α-mannosidases, may serve as a key inhibitor of glycoprotein biosynthesis. Its inhibitory effect may lead to high mannose glycoproteins in cell culture.

AR524 是一种转基因抑制剂，抑制活性高于已知的转基因抑制剂 kifunensine。AR524 能够抑制低浓度 (10 μM) 的人类恶性细胞球状体的形成。