keratitis

Pranoprofen (Pyranoprofen) 可抑制COX1/2酶，阻断花生四烯酸转化为二十烷醇，减少前列腺素的合成。它是一种用于眼科的非甾体抗炎试剂。

CAY10650 是高效的胞浆磷脂酶A2α抑制剂，IC50=12 nM，能够抑制脂滴形成和 PGE2 分泌。

RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) 抑制肽（TFA）抑制金黄色葡萄球菌，对蜂窝织炎、角膜炎、化脓性关节炎、骨髓炎和乳腺炎等疾病有效。

Hexamidine 具有抗阿米巴原虫的活性，可用于研究棘阿米巴角膜炎 (Acanthamoebakeratitis)。

Hexamidine diisethionate 是一种抗微生物剂，专门针对Acanthamoeba原生动物。它在Acanthamoeba角膜炎等眼部感染性疾病的研究中展现出潜力。

Vasoactive intestinal peptide 是 VPAC1/VPAC2 receptor (G 蛋白偶联受体) 的激动剂。在铜绿假单胞菌诱导的角膜炎模型中，该化合物能降低角膜穿孔率和细菌载量，同时抑制过度的中性粒细胞浸润。Vasoactive intestinal peptide 增强抗炎介质如 IL-10 和 TGF-β，并抑制促炎因子如 IL-1β 和 TNF-α。此外，它还能上调 SOCS3、COX-2、ALOX12 等脂质介质相关酶，促进炎症消退。该化合物有望用于眼部感染性疾病的研究。

Propamidine isethionate是一种二脒类（diamidine）化合物，具有显著的抗菌和抗原虫活性。它是临床和实验室研究中治疗棘阿米巴角膜炎（Acanthamoeba keratitis）的关键试剂。Propamidine 通过与 DNA 结合干扰病原体的核酸合成，从而发挥其杀伤作用。

Idoxuridine hydrate (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is a competitive inhibitor of phosphorylases. As an iodinated thymidine analogue, it effectively inhibits DNA polymerase and hinders viral replication, making it useful in the treatment of viral eye infections such as herpes simplex keratitis. Against feline herpesvirus, Idoxuridine has been found to have an IC50 value of 4.3 μM [1].

Eprociclovir dihydrate is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinical scores and suppressed virus growth. Eprociclovir is a promising alternative treatment of herpetic keratitis.

Eprociclovir Na is the salt form of Eprociclovir, also known as A-5021, a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinical scores and suppressed virus growth. Eprociclovir is a promising alternative treatment of herpetic keratitis.

Eprociclovir potassium is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinical scores and suppressed virus growth. Eprociclovir is a promising alternative treatment of herpetic keratitis.

Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1) 是来自小鼠的、靶向小鼠4-1BBL/CD137L的抗体抑制剂,能够阻断 4-1BB 配体（4-1BBL），进而抑制 CD4+ 和 CD8+ T 细胞的活性，适用于癌症、感染、炎症及免疫学相关研究，具体可应用于 MC38 肿瘤、淋巴细胞性脉络丛脑膜炎病毒（LCMV）感染、疱疹性基质性角膜炎（HSK）等模型。

Nucleoside Derivatives - 2’,3’-Dideoxy nucleosides; Halo-nucleosides; 5-Modified pyrimidine nucleosides; Drugs and Inhibitors; 气管炎病毒检定tracheitis virus test。治疗单纯疱诊性病毒角膜炎herpes simplex keratitis drug