jnj4796

JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).

JNJ-47965567 (JNJ-479655) 是中枢通透性、高亲和力、选择性的P2X7拮抗剂，可用于探讨中枢 P2X7 在中枢神经系统病理生理模型中的作用。它对人和大鼠 P2X7 作用的pKi 值分别为 7.9 和 8.7。