1-Methyl-4-imidazoleaceticacid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.
Pi-Methylimidazoleaceticacid, considered a potential neurotoxin, targets the nervous system and may pose significant health risks when absorbed or metabolized within biological systems.