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gusacitinib

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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
  • Gusacitinib
    ASN-002
    T143311425381-60-7
    Gusacitinib (ASN-002) 是一种有效的 SYK 激酶和JAK 激酶的双抑制剂，IC50值为 5 到 46 nM 之间，具有抗癌活性。
    JAKSyk
    • ¥ 273
    现货
    规格
    数量
    TargetMol | Inhibitor Sale
  • Gusacitinib HCl
    T697662228989-14-6
    Gusacitinib, also known as ASN-002 and EN-3351, is a potent dual inhibitor of SYK JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed the SYK and JAK family kinase signaling pathways as measured in pLAT and pSTAT assays, respectively. When profiled in a panel of 178 cell lines, ASN002 showed strong anti-proliferative activity in many lymphoid leukemia cell lines, including SU-DHL-6, SU-DHL-4, OCI-LY10, H929 and Pfeiffer.
    Others
    • ¥ 10600
    1-2周
    规格
    数量
  • NPD-039
    T697652229043-40-5
    NPD-039 is an inhibitor of trypanosoma brucei phosphodiesterase B1 (TbrPDEB1).
    Others
    • ¥ 10600
    6-8周
    规格
    数量