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  • Epigenetic Reader Domain
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TargetMol产品目录中 "gne987"的结果
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TargetMol产品目录中 "

gne987

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  • 抑制剂&激动剂
    2
    TargetMol | Inhibitors_Agonists
  • PROTAC
    2
    TargetMol | PROTAC
  • GNE-987
    T114412417371-71-0
    GNE-987 is a highly active chimeric BET degrader. GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50: 4.7 and 4.4 nM, respectively). GNE-987 exhibits picomolar cell BRD4 degradation activity (DC50: 0.03
    Epigenetic Reader DomainPROTACs
    • ¥ 4950
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  • (s)-gne-987
    T12798
    (S)-GNE-987 binds to the BRD4 BD1(IC50=4 nM) and BD2 (3.9 nM) bromodomains and can be used to design PROTAC-Antibody Conjugate (PAC).
    Epigenetic Reader Domain
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