glur 6

GluR6 antagonist-1 抑制酪氨酸激酶 p56lck SH2 结构域的 pY 结合位点。

DCG-IV is an effective agonist of class II mGluR. DCG-IV has anticonvulsant and neuroprotective effects. The EC50 of mGlu2R and mGlu3R are 0.35 and 0.09 μM, respectively. DCG-IV is also a competitive antagonist of Group I (IC50: mGlu1 / 5R = 389/630 μM) a

L-Cysteinesulfinic acid 是一种内源性的神经递质，对多种代谢型谷氨酸受体（mGluRs）具有激动作用，包括mGluR1，mGluR2，mGluR4，mGluR5，mGluR6 和 mGluR8，pEC50 = 2.7~4.0。L-Cysteinesulfinic acid是pld偶联代谢兴奋性氨基酸（EAA）受体的激动剂。

L-Cysteinesulfinic acid monohydrate 是代谢型谷氨酸受体 (mGluRs) 的有效激动剂，可以作用于 mGluR1，mGluR2，mGluR5，mGluR4，mGluR6 和 mGluR8，pEC50分别为 3.92，3.9，4.6，2.7，4.0，和 3.94。