Neuromuscular Disorder-Targeting Compound 1 is utilized in research for neuromuscular disorders, including chronic fatigue syndrome and fibromyalgia syndrome symptoms.
RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue. RX 67668 is an effective cholinesterase inhibitor (IC50: 5 μM for both acetylcholinesterase and butyrylcholinesterase). RX 67668 can reverse the neuromuscular blockade induced by D-tub
Dalapon is a selective herbicide used to control perennial grasses. The major use of dalapon is on food crops including sugarcane and sugar beets. Its use is no longer authorized in France. The National Institute for Occupational Safety and Health in the
Palmitoylcholine is an acyl choline.1It inhibits protein kinase C activity when used at a concentration of 100 μM.2Palmitoylcholine induces hemolysis in rat erythrocytes.3Plasma levels of palmitoylcholine are decreased in female patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).1
1.Germain, A., Barupal, D.K., Levine, S.M., et al.Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl lipids and steroidsMetabolites10(1)34(2020) 2.Nakadate, T., and Blumberg, P.M.Modulation by palmitoylcarnitine of protein kinase C activationCancer Res.47(24 Pt 1)6537-6542(1987) 3.Cho, K.S., and Proulx, P.Interactions of acyl carnitines and other lysins with erythrocytes and reconstituted erythrocyte lipoproteinsBiochim. Biophys. Acta318(1)50-60(1973)
D-Ribose(mixture of isomers)-13C5 是经过 13C 标记的 D-Ribose(mixture of isomers)。作为一种能量增强剂,D-Ribose(mixture of isomers) 是 ATP 的糖成分,广泛应用于作为慢性疲劳综合症及心肌能量代谢疗法的补充剂。它在蛋白质糖化过程中具有活性,并能通过 RAGE 依赖的途径诱导 NF-κB 炎症。