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抑制剂&激动剂
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TargetMol产品目录中 "dbco amine"的结果
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TargetMol产品目录中 "

dbco amine

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  • 抑制剂&激动剂
    25
    TargetMol | Inhibitors_Agonists
  • 染料试剂
    1
    TargetMol | Dye_Reagents
  • PROTAC
    18
    TargetMol | PROTAC
  • 分子与细胞研究
    2
    TargetMol | Inhibitors_Agonists
  • DBCO-amine
    T150581255942-06-3
    DBCO-amine 是一种可切割的 ADC 接头,用于合成抗体-药物偶联物。
    • ¥ 108
    In stock
    规格
    数量
    TargetMol | Inhibitor Sale
  • Sulfo DBCO-amine
    T169562028284-70-8
    Sulfo DBCO-amine is an alkyl chain-derived PROTAC linker utilized for synthesizing PROTACs[1].
    • 待询
    规格
    数量
  • DBCO-NHCO-PEG4-amine
    T150621255942-08-5
    DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) [1].
    • ¥ 2870
    2-4周
    规格
    数量
  • DBCO-PEG4-amine
    T150681840886-10-3
    DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1].
    • ¥ 636
    5日内发货
    规格
    数量
  • Sulfo DBCO-PEG4-amine
    T169572055198-05-3
    Sulfo DBCO-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-C2-PEG4-amine
    T17744
    DBCO-C2-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-C3-PEG4-amine
    T17746
    DBCO-C3-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-NHCO-PEG12-amine
    T17758
    DBCO-NHCO-PEG12-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-NHCO-PEG2-amine
    T17763
    DBCO-NHCO-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-NHCO-PEG6-amine
    T17770
    DBCO-NHCO-PEG6-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-PEG1-amine
    T177772364591-79-5
    DBCO-PEG1-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-PEG2-amine
    T177862250216-96-5
    DBCO-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • ¥ 788
    5日内发货
    规格
    数量
  • DBCO-PEG6-amine
    T178052353409-98-8
    DBCO-PEG6-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • DBCO-PEG9-amine
    T178082353409-99-9
    DBCO-PEG9-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • ¥ 720
    5日内发货
    规格
    数量
  • DBCO-SS-amine
    T178122742923-58-4
    DBCO-SS-amine is a cleavable linker vital in ADC synthesis. DBCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • DBCO-PEG3-amine
    DBCO-PEG3-amine
    T395092093409-57-3
    DBCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
    规格
    数量
  • Azido-PEG10-amine
    叠氮十聚乙二醇氨基
    T14414912849-73-1
    Azido-PEG10-amine是一种不可降解(non-cleavable)的ADC linker和PEG类的PROTAC linker,可用于合成抗体偶联分子(ADC)和PROTAC,可以和含有Alkyne、DBCO或BCN基团的分子发生点击化学反应。
    • ¥ 137
    In stock
    规格
    数量
  • Azido-PEG7-amine
    氨基-七聚乙二醇-叠氮
    T144751333154-77-0
    Azido-PEG7-amine是一种不可降解(non-cleavable)的ADC linker和PEG类的PROTAC linker,可用于合成抗体偶联分子(ADC)和PROTAC,可以和含有Alkyne、DBCO或BCN基团的分子发生点击化学反应。
    • ¥ 142
    In stock
    规格
    数量
  • diABZI-V/C-DBCO
    T200187
    diABZI-V C-DBCO(Compound 3)作为一种高效的STING激动剂,通过组织蛋白酶B的作用释放diABZI-胺,激活STING,从而使干扰素及其他免疫激活分子的生成得以提高,有效增强免疫系统对肿瘤的攻击能力。在THP1-Dual细胞中,diABZI-V C-DBCO与diABZI-胺激活STING的EC50值分别为1.47 nM和0.144 nM;在原代小鼠脾细胞中,这些值分别为7.7 μM和0.17 μM。因此,diABZI-V C-DBCO在癌症免疫研究领域具有重要的应用价值。
    • 待询
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  • 3-Azidopropionic Acid Sulfo-NHS Ester
    T293892055198-09-7
    3-Azidopropionic Acid Sulfo-NHS Ester is a water-soluble compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the p
    • ¥ 2508
    3-6月
    规格
    数量
  • Sulfo DBCO-TFP Ester
    T878112268816-76-6
    Sulfo DBCO-TFP Ester 是一种水溶性、含有磺基的点击化学试剂,可将磺基 DBCO 部分简单高效地掺入到含胺分子上。
    • ¥ 11800
    4-6周
    规格
    数量
  • DBCO-PEG24-acid
    T896632765066-36-0
    DBCO-PEG24-acid 是一种独特的点击化学试剂,作为带有 PEG 连接子的 DBCO-acid 的衍生物,并含有 DBCO 基团.这种 DBCO 基团因其高能量的应变促进特性,常被用于无铜点击化学反应.其亲水性的聚乙二醇链增强了水溶性.此外,该化合物的末端羧酸可在 EDC 或 HATU 等激活剂存在下与伯胺基团反应,形成稳定的酰胺键.产品为试剂级,仅限研究使用.
    • 待询
    规格
    数量
  • Sulfo DBCO-PEG3-acid
    T896862566404-75-7
    Sulfo DBCO-PEG3-acid 是一种具备叠氮基团的点化学试剂,是DBCO-acid的衍生物,它包含了一个PEG连接剂和DBCO基团.DBCO基团以其应变促进的高能量特性,经常被应用于无铜点击化学反应中.其亲水性的聚乙二醇链和硫基极大地提高了其水溶性.该化合物的末端羧酸在激活剂(如 EDC 或 HATU)存在下能与伯胺基团发生反应,生成酰胺键.该产品为试剂级,仅限研究使用.
    • 待询
    10-14周
    规格
    数量
  • DBCO-PEG4-Val-Cit-PAB-PNP
    TYD-018602226472-28-0
    DBCO-PEG4-Val-Cit-PAB-PNP 是一种可裂解的 ADC 连接子,其中 Val-Cit 可以被 Cathepsin B 特异性裂解,而 PNP 可以被含胺的有效载荷取代。DBCO 能与叠氮化物分子通过点击化学反应结合。
    • 待询
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