d-glucose 6-phosphate

D-Glucose 6-phosphate (D-葡萄糖-6-磷酸)是6号碳上的羟基被己糖激酶磷酸化的葡萄糖，参与糖酵解、糖异生和戊糖磷酸途径，也可以转化为糖原或淀粉储存。在肝脏中作为葡萄糖6-磷酸酶的底物，在内质网腔中作为己糖6-磷酸脱氢酶（H6PDH）的底物。

D-Glucose 6-phosphate disodium salt 广泛存在于生物提内的化合物，是葡萄糖第 6 号碳经过磷酸化后生成的分子，参与磷酸戊糖途径与糖酵解途径等体内多种多种代谢调节途径。

2-Deoxy-D-glucose 6-phosphate disodium 是一种葡萄糖类似物，可抑制糖酵解，抑制己糖激酶和葡萄糖-6-磷酸异构酶的功能。

D-Glucose 6-phosphate sodium (G6P sodium salt) 是内源性代谢产物的一种。

D-Glucose 6-Phosphate Barium Salt Heptahydrate是一种高纯度生化试剂，适合作为生物材料或有机合成中间体，广泛应用于生命科学领域的研究与实验。

5-Thio-D-glucose-6-phosphate diammonium salt 是一种用于糖生物学研究的生化试剂。糖生物学专注于研究糖的结构、合成、生物学以及进化过程。它涵盖了碳水化合物化学、聚糖形成与降解的酶学机制、蛋白质-聚糖的识别以及聚糖在生物体系中的功能。该领域与基础研究、生物医学和生物技术紧密相连。

D-Glucose-6-phosphate (dipotassium hydrate) 是一种用于研究糖生物学的生化试剂。糖生物学关注糖的结构、合成、生物学和进化，包括碳水化合物化学、聚糖的形成与降解的酶学、蛋白质与聚糖的识别以及聚糖在生物系统中的功能。该领域与基础研究、生物医学及生物技术密切相关。

D-Fructose-6-phosphate (sodium salt hydrate) 是由磷酸葡萄糖异构酶将 6-磷酸葡萄糖异构化产生的糖酵解途径的糖中间体，可用于研究癌症。

2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B osteosarcoma cells cultured under hypoxic conditions when used at a concentration of 2 mg ml.4,5In vivo, 2-deoxy-D-glucose (500 mg kg) reduces tumor growth in 143B osteosarcoma and MV522 non-small cell lung cancer mouse xenograft models when used alone or in combination with doxorubicin or paclitaxel .6 1.Kang, H.T., and Hwang, E.S.2-Deoxyglucose: An anticancer and antiviral therapeutic, but not any more a low glucose mimeticLife Sci.78(12)1392-1399(2006) 2.Aft, R.L., Zhang, F.W., and Gius, D.Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: Mechanism of cell deathBr. J. Cancer87(7)805-812(2002) 3.Ralser, M., Wamelink, M.M., Struys, E.A., et al.A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growthProc. Natl. Acad. Sci. USA105(46)17807-17811(2008) 4.Liu, H., Savaraj, N., Priebe, W., et al.Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: A strategy for solid tumor therapy (Model C)Biochem. Pharmacol.64(12)1745-1751(2002) 5.Zhang, X.D., Deslandes, E., Villedieu, M., et al.Effect of 2-deoxy-D-glucose on various malignant cell lines in vitroAnticancer Res.26(5A)3561-3566(2006) 6.Maschek, G., Savaraj, N., Priebe, W., et al.2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivoCancer Res.64(1)31-34(2004)

The specific growth rates of C. raciborskii cells in media treated with β-glycerol phosphate, d-glucose-6-phosphate, and (2-aminoethyl)phosphinic acid are significantly higher than those of cells grown in phosphorus free media.

D-Glucose-6-phosphate dipotassium salt dihydrate 是通过在葡萄糖的第6号碳上进行磷酸化得到的化合物.它在生物细胞内广泛存在,主要参与磷酸戊糖途径和糖酵解等关键生化过程.

D-Fructose 6-phosphate dipotassium 是唾液中的一种内源代谢物，参与影响细胞生长和自噬，并可以通过 Fructose-1,6-bisphosphatase (FBPase) 水解获得。在磷酸葡萄糖异构酶的催化下，可以转化为 D-glucose 6-phosphate (HY-112537)。作为糖酵解 (Glycolysis) 途径与磷酸戊糖途径 (Pentose Phosphate Pathway) 的糖中间体，D-Fructose 6-phosphate dipotassium 可用于研究路易体痴呆。

D-Fructose-6-phosphate disodium salt (D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT) 是内源性代谢产物的一种。

α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabolism by glucose 1,6-bisphosphate in extrahepatic tissues; comparison with fructose 2,6-bisphosphateInt. J. Biochem.22(6)553-557(1990) 2.Maliekal, P., Sokolova, T., Vertommen, D., et al.Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the α-D-phosphohexomutase familyJ. Biol. Chem.282(44)31844-31851(2007) 3.Moustafa, H.M.A., Zaghloul, T.I., and Zhang, Y.-H.P.A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritimaAnal. Biochem.50175-81(2016) 4.Panosian, T.D., Nannemann, D.P., Watkins, G.R., et al.Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycleJ. Biol. Chem.286(10)8043-8054(2011)

α-D-Glucose 1-phosphate disodium salt hydrate 是合成葡萄糖醛酸的起始原料。它可用作心脏病研究所必需的细胞抑制剂、抗生素、免疫抑制剂和循环系统研究材料。