cervical carcinoma cell

Tyrphostin B44, (+) enantiomer 是一种表皮生长因子受体 (EGFR) 激酶抑制剂，IC50 为 0.86 μM，活性低于 (-) 对映体。

β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。

Ganoderic acid F 是一种灵芝酸。它具有抗肿瘤和抗转移的活性，与抑制血管生成和涉及细胞增殖和细胞死亡，致癌作用，氧化应激，钙信号传导和内质网应激的蛋白质改变等机制相关。

BPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was potent in targeting a variety of cancer cell lines regardless of the tissue origin, p53 status, or expression of MDR1. At the cellular level, BPR1K653 induced endo-replication and subsequent apoptosis in both MDR1-negative and MDR1-positive cancer cells. Importantly, it showed potent activity against the growth of xenograft tumors of the human cervical carcinoma KB and KB-derived MDR1-positive KB-VIN10 cells in nude mice. Finally, BPR1K653 also exhibited favorable pharmacokinetic properties in rats., BPR1K653 is a promising anti-cancer compound that has potential for the management of various malignancies, particularly for patients with MDR1-related drug resistance after prolonged chemotherapeutic treatments.

Lirilumab (IPH2102) 是一种针对杀伤性免疫球蛋白样受体抗体 KIR2D 的抗体，具有抗肿瘤活性，通过 Vav1 依赖性 NF-κB 去抑制增强自然杀伤细胞的抗 HPV+ 宫颈癌活性，可用于研究白血病、头颈部鳞状细胞癌 (SCCHN)。

17-Hydroxyneomatrine 是一种从苦参 (Sophora flavescens) 提取的化合物，有效抑制人宫颈癌Hela细胞生长，并展现抗菌、抗过敏、抗肿瘤、抗心律失常、消肿、利尿、免疫调节等多种生物活性。

Ganolucidic acid E effectively suppresses the proliferation of three human cancer cell lines: Caco-2 (colon cancer), HepG2 (hepatocellular carcinoma), and HeLa (cervical cancer).

Albiducin A 是一种在 Hymenoscyphus albidus 中发现的抗生素，拥有抗菌和抗癌特性。其对细菌和真菌的 MIC 范围为 16.7-66.7 mg mL；对小鼠成纤维细胞系 (Mouse fibroblasts L929) 和人宫颈癌细胞系 (Human cervical carcinoma cell line KB3-1) 的 IC50 分别为 6.1 和 2.7 μg mL。Albiducin A 有潜力在感染和癌症相关研究中发挥作用。