cd 256

Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B TACI and to TNFRSF17 BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.

The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFFR.

Expression system: HEK293 Cells
Length: 112-250, Partial
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 112-250, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 112-250, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 112-250, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 96-241, Full Length of Mature Protein
Activity: ELISA