azido-peg-2-azide

Azido-PEG2-azide 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Azido-PEG4-CH2-Boc is a four-unit cleavable polyethylene glycol (PEG) linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2]. This linker is characterized by its azide functional group and PEG backbone, facilitating the conjugation of drugs to antibodies in ADC development and enabling the synthesis of PROTACs utilizing PEG and alkyl ether moieties.

Bocaminooxyacetamide-PEG2-Azido 是一种可降解的含2个单元PEG的ADC linker，可用于合成抗体偶联活性分子 (ADC)。作为点击化学试剂，它含有Azide基团，可以与含Alkyne基团的分子进行铜催化叠氮-炔环加成反应（CuAAc），也可以与含DBCO或BCN基团的分子进行菌株促进的炔-叠氮环加成反应 (SPAAC)。