Azido-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG2-hydrazide-Boc is a polyethylene glycol (PEG) derivative serving as a linker in the development of proteolysis targeting chimeras (PROTACs) [1].
Azido-PEG4-CH2-Boc is a four-unit cleavable polyethylene glycol (PEG) linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2]. This linker is characterized by its azide functional group and PEG backbone, facilitating the conjugation of drugs to antibodies in ADC development and enabling the synthesis of PROTACs utilizing PEG and alkyl ether moieties.
Azido-PEG4-hydrazide-Boc is a polyethylene glycol (PEG)-based bifunctional linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
N-(Azido-PEG2)-N-bis(PEG4-Boc) is a polyethylene glycol (PEG)-based PROTAC linker, employed for the efficient synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
N-(Azido-PEG2)-N-Boc-PEG4-acid is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
N-(Azido-PEG3)-N-Boc-PEG3-acid is a polyethylene glycol (PEG)-based linker specifically designed for the construction of proteolysis-targeting chimeras (PROTACs)[1].
N-(Azido-PEG4)-N-Boc-PEG4-Boc is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker featuring a terminal azide group. It is commonly employed in the synthesis of PROTACs[1].
N-(Azido-PEG3)-N-bis(PEG4-Boc) is a polyethylene glycol (PEG) derivative specifically designed as a linker for PROteolysis TArgeting Chimeras (PROTACs)[1].
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker for the development of proteolysis targeting chimeras (PROTACs)[1].