ar12

Osu03012 (AR-12) 是一种口服生物可利用的小分子塞来昔布衍生的磷酸肌醇依赖性激酶 1(PDK1) 抑制剂，具有潜在的抗肿瘤活性。

SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.

SAR125844 是高度选择性可逆ATP 竞争性的MET 受体酪氨酸激酶抑制剂，其IC50值为4.2 nM。能抑制细胞中MET 的自磷酸化。

SAR125884 hydrochlorid (1116743-46-4(free base)) 是一种有效的选择性 MET 激酶抑制剂，具有良好的临床前毒性特征 (IC50=4.2 nM)。

Trapidil (Avantrin) 是一种抗血小板药物，是一种血管扩张剂，有特异性血小板衍生生长因子。

AR-12456 is a Trapidil derivative that prevents serum hyperlipidemia in guinea pigs.

AR 12465 is a trapidil derivative which may affect LDL receptor mediated uptake and degradation of 125 I-LDL by human skin fibroblasts (HSF) and human hepatic cells (HEP G2).

AR 12463 是一种曲匹地尔衍生物，可显着减少血清总胆固醇的增加。

APX2009 is a second-generation APE1 Ref-1 redox-specific inhibitor. APX2009 significantly reduces NFkB transcriptional activity, survivin mRNA, and survivin protein levels. APX2009 decreases prostate cancer cell proliferation and induces cell cycle arrest.

20S,24R-Epoxydammar-12,25-diol-3-one是一种天然产物，属于松科金钱松属，其产品编号为 TN2803，CAS号为 25279-15-6。20S,24R-Epoxydammar-12,25-diol-3-one可用作对照参考。