anti-tnbc agent-1

anti-TNBC agent-1 is a highly effective compound specifically designed to target and combat triple-negative breast cancer (TNBC). It demonstrates remarkable potency against various breast cancer cell types, with IC50 values spanning from 0.20 μM to 0.27 μM. The mechanism of action of anti-TNBC agent-1 involves inducing apoptosis in SUM-159 cells through the mitochondria pathway, as well as causing G1 phase arrest in these cells.

anti-TNBC agent-10 是一种针对三阴性乳腺癌 (TNBC) 的药剂。它在 BT549 细胞中展现出显著的活性 (IC50= 0.018 μM)，对 MDA-MB-231 细胞也保持一定效能 (IC50= 4.16 μM)。在移植了 MDA-MB-231 TNBC 皮下异种移植瘤的小鼠模型中，anti-TNBC agent-10 显示出强大的抗肿瘤效果。anti-TNBC agent-10 是研究 TNBC 的一种重要工具。