Cat. No.	Product Name	Target	Signaling Pathways
T13278	Valecobulin hydrochloride	Microtubule Associated	Cytoskeletal Signaling
	Valecobulin hydrochloride (CKD-516 hydrochloride) is a valine prodrug of S516 and a vascular disrupting agent (VDA). It is a potent inhibitor of β-tubulin polymerization, and with marked antitumor activity against murine and human solid tumors.
T4327	Prexasertib dihydrochloride	S6 Kinase; Apoptosis; Chk	Apoptosis; MAPK; Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling
	Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.
T4310	Prexasertib	Apoptosis; Chk	Apoptosis; Cell Cycle/Checkpoint
	Prexasertib is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
T12823	S516	Microtubule Associated	Cytoskeletal Signaling
	S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.
T13278L	Valecobulin	Others	Others
	Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.

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