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Search Results for " oxindole "
Targets Recommended: VEGFR

8

抑制剂 & 化合物

7

天然产物

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Cat. No. Product Name Target Signaling Pathways
T22755 (E)-FeCP-oxindole

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂,IC50 为 214 nM。
T23554 (Z)-FeCP-oxindole

VEGFR; Others Angiogenesis; Others; Tyrosine Kinase/Adaptors
(Z)-FeCP-oxindole 是 VEGFR2 的选择性抑制剂,对人类的 IC50 为 200 nM。 (Z)-FeCP-oxindole 具有抗癌活性。
T0538 3-Methylindolin-2-one

3-Methyloxindole,3-Methyl-2-oxindole,3-甲基羟基吲哚

Others; Endogenous Metabolite; AChE Metabolism; Neuroscience; Others
3-Methyloxindole 是一种酚类病毒诱导剂,是一种乙酰胆碱酯酶抑制。
T26126 Roxindole

EMD 49980

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Roxindole (EMD 49980) 是一种选择性多巴胺自身受体和 5-HT1A 双重激动剂,也是5-羟色胺 (5-HT) 的摄取的抑制剂,具有抗精神病和抗抑郁活性。Roxindole 可用于研究帕金森和神经分裂。
T23250 Roxindole hydrochloride

Others Others
Dopamine D2 autoreceptor agonist
T17263 XEN907

Others Others
XEN907 is a novel spiro oxindole NaV1.7 blocker. XEN907 also inhibits hNaV1.7 (IC50: 3 nM).
T9853 STING activator Compound 53

STING Immunology/Inflammation
基于 oxindole 核心结构的 STING activator Compound 53 在永生化细胞和原代细胞中表现出强大的 STING(人 EC50 185 nM)的靶向功能激活以及与 STING 激活一致的细胞因子诱导指纹。
T61379 Anticancer agent 30

Others Others
Anticancer agent 30 (compound 6f-Z) is a potent anticancer compound. It belongs to the class of 3-arylidene-2-oxindole derivatives and acts as a selective inhibitor of CDK2. Extensive research has demonstrated its significant anticancer activity, making it a promising candidate for cancer treatment [1].

化合物

(E)-FeCP-oxindole
Cat.No: T22755
Synonym:
Target: VEGFR
(Z)-FeCP-oxindole
Cat.No: T23554
Synonym:
Target: VEGFR, Others
3-Methylindolin-2-one
Cat.No: T0538
Synonym: 3-Methyloxindole,3-Methyl-2-oxindole,3-甲基羟基吲哚
Target: Others, Endogenous Metabolite, AChE
Roxindole
Cat.No: T26126
Synonym: EMD 49980
Target: Dopamine Receptor, 5-HT Receptor
Roxindole hydrochloride
Cat.No: T23250
Synonym:
Target: Others
XEN907
Cat.No: T17263
Synonym:
Target: Others
STING activator Compound 53
Cat.No: T9853
Synonym:
Target: STING
Anticancer agent 30
Cat.No: T61379
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
Fr16741 Oxindole

2-吲哚酮,板蓝根,Indolin-2-one

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Oxindole (Indolin-2-one) 是一种芳族杂环砌块,其衍生物是激酶抑制剂研究中的主要成分。
T5S0658 Corynoxine

柯诺辛,柯诺辛碱

Autophagy Autophagy
Corynoxine 是从大叶钩藤中分离出的一种四环羟吲哚生物碱。它是一种自噬增强剂,可通过Akt/mTOR 途径促进 α-突触核蛋白的清除。
TN2938 3-Hydroxy-3-acetonyloxindole

Others Others
3-Hydroxy-3-acetonyloxindole是一种天然产物,属于萝藦科牛奶菜属,其产品编号为 TN2938,CAS号为 33417-17-3。3-Hydroxy-3-acetonyloxindole可用作对照参考。
T37710 5-Hydroxyoxindole

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
5-Hydroxyoxindole 是尿酸的一种结构类似物,具有脂质过氧化抑制活性和自由基 DPPH 清除活性,可用于氧化应激介导的疾病的研究。
T5143 Corynoxine hydrochloride(6877-32-3(free base))

Autophagy Autophagy
Corynoxine hydrochloride(6877-32-3(free base)) 是一种天然羟吲哚生物碱,可在不同的神经元细胞系(包括 N2a 和 SHSY-5Y 细胞)中诱导自噬。
T34259 Rankinidine

Others Others
Rankinidine, as an oxindole alkaloid, is isolated from Gelsemium rankinii.
T75438 Corynoxine hydrochloride

Others Others
Corynoxine hydrochloride 是一种从Uncaria macrophylla 中分离出的四环羟吲哚生物碱。Corynoxine hydrochloride 是一种天然的自噬增强剂,可通过Akt/mTOR 途径促进 α-突触核蛋白的清除。

天然产物

Oxindole
Cat.No: Fr16741
Synonym: 2-吲哚酮,板蓝根,Indolin-2-one
Target: Others, HIV Protease
Corynoxine
Cat.No: T5S0658
Synonym: 柯诺辛,柯诺辛碱
Target: Autophagy
3-Hydroxy-3-acetonyloxindole
Cat.No: TN2938
Synonym:
Target: Others
5-Hydroxyoxindole
Cat.No: T37710
Synonym:
Target: Reactive Oxygen Species
Corynoxine hydrochloride(6877-32-3(free base))
Cat.No: T5143
Synonym:
Target: Autophagy
Rankinidine
Cat.No: T34259
Synonym:
Target: Others
Corynoxine hydrochloride
Cat.No: T75438
Synonym:
Target: Others
TargetMol Loading
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