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Search Results for " kras-1 "

Targets Recommended: Ras

69

抑制剂 & 化合物

1741

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11776	KRas G12C inhibitor 1	Ras	GPCR/G Protein; MAPK
	KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
T9674	KRAS G12D inhibitor 1
	KRAS G12D inhibitor 1 (例 243) 是一种KRAS G12D 抑制剂，对KRAS G12D 介导的 ERK 磷酸化的IC50值为0.8 nM。
T40272	KRAS mutant protein inhibitor 1
	KRAS mutant protein inhibitor 1 is a KRAS mutant protein inhibitor for potential treatment in cancer.
T8418	DCLK1-IN-1	Others	Others
	DCLK1-IN-1 是选择性的、体内相容的双皮质素样激酶1DCLK1激酶结构域化学探针。它抑制 DCLK1 和 DCLK2 激酶。它具有低毒性，可以研究 DCLK1 的生物学特性，确定其在肿瘤中的作用，如 DCLK1+胰腺导管腺癌。
T11224	Rineterkib ERK-IN-1	ERK; Raf	MAPK
	Rineterkib (ERK-IN-1) 是口服有效的RAF 和ERK1/2的抑制剂，与 KRAS-突变型非小细胞肺癌、BRAF-突变型非小细胞肺癌、KRAS-突变型胰腺癌、KRAS -突变型结肠癌和 KRAS-突变型卵巢癌尤为相关。
T77805	KRAS G12C mutant protein inhibitor A-1
	KRAS G12C mutant protein inhibitor A-1 可用于 Ras 相关研究。
T15735	Leptomycin B CI 940,LMB,来普霉素B	CRM1; Antibiotic; Antifungal	Membrane transporter/Ion channel; Microbiology/Virology
	Leptomycin B (LMB) 是一种抗真菌抗生素，可阻断真核细胞周期，抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。它
T13844	PROTAC K-Ras Degrader-1	Ras	GPCR/G Protein; MAPK
	PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
T9533	BC-LI-0186 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) 是选择性抑制亮氨酸 tRNA 合成酶与 Ras 相关的 GTP 结合蛋白 D 相互作用(IC50=46.11 nM)。BC-LI-0186能有效抑制肿瘤相关 MTOR 突变体的特性和雷帕霉素耐药癌细胞的生长，能够用于肺癌的相关研究。
T18054	K-Ras ligand-Linker Conjugate 1	Others	Others
	K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
T79147	KRAS degrader-1
	KRAS degrader-1（compound 1）是通过自噬-溶酶体途径降解特定蛋白的高效KRAS降解剂。
T11735	K-Ras G12C-IN-1	Phosphatase	Metabolism
	K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
T79162	SOS1/KRAS-IN-1	Ras	GPCR/G Protein; MAPK
	SOS1/KRAS-IN-1(Compound 2)为针对SOS1/KRAS介导的疾病进行研究而设计的抑制剂。
T79072	KRAS G12D modulator-1	Ras	GPCR/G Protein; MAPK
	KRAS G12D modulator-1（compound 6）是高效KRAS G12D调节剂，NEA-G12D、PPI-G12D 和 pERK-AGS的IC50范围为1-10 μM，适用于癌症研究。
T74973	KRas G12R inhibitor 1
	KRas G12R inhibitor 1 (compound 3) 是一种 KRas G12R 选择性共价抑制剂，可以利用突变半胱氨酸的强亲核性，在 K-Ras 的 Switch II 区域不可逆结合。KRas G12R inhibitor 1 可用于癌症研究。
T77926	PROTAC KRAS G12C degrader-1	PROTACs	PROTAC
	PROTACKRAS G12C degrader-1是基于Cereblon的KRASG12C PROTAC降解剂，能诱导CRBN/KRASG12C二聚化，并在报告细胞中降解GFP-KRASG12C。
T11282	FGTI-2734	Transferase	Metabolism
	FGTI-2734 是有效的RAS C-末端法尼基转移酶 (FT) 和香叶烯基转移酶-1 (GGT-1) 抑制剂，IC50s 分别为 250 nM 和 520 nM。它可以阻断 KRAS 的膜定位，从而解决 KRAS 耐药性问题，并抑制突变的 KRAS 胰腺肿瘤。
T12979	BI-3406	p38 MAPK; MAPK; Ras	GPCR/G Protein; MAPK
	BI-3406 是一种可口服、高效且选择性的 KRAS-SOS1 抑制剂，具有抗癌活性。它有效减少 GTP 加载的 KRAS 的形成，抑制 MAPK 信号通路。它还抑制 KRAS 与 SOS1之间相互作用，IC50为 6 nM。
T78170	Kras4B G12D-IN-1	Ras	GPCR/G Protein; MAPK
	Kras4B G12D-IN-1为Kras4B G12D的抑制剂，表现出抗癌活性。在降低Kras4B G12D表达的小鼠胚胎成纤维细胞(MEF)中减少Kras蛋白水平。
T81263	RMC-7977	Ras	GPCR/G Protein; MAPK
	RMC-7977是一种可逆的三重复合RAS抑制剂，对KRAS、NRAS和HRAS的突变型及野生型(WT)变体表现出广谱活性。该化合物能够引发肿瘤消退，在多种依赖RAS的临床前癌症模型中显示出良好的耐受性。此外，RMC-7977还能有效抑制KRASG12C癌瘤模型的生长。[1]
T7123	AMG-47a	VEGFR; p38 MAPK; JAK; Src	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors
	AMG-47a 是具有口服活性的 Lck 抑制剂，IC50值为 0.2 nM。它具有抗炎作用，对 VEGF2、p38α、p38α、Jak3、MLR 和 IL-2的 IC50值分别为 1、3、72、30 和 21 nM。
T6843	GDC-0623 G-868,GDC0623,RG 7421,MEK inhibitor 1	Apoptosis; MEK	Apoptosis; MAPK
	GDC-0623 (RG 7421) 是一种 ATP 竞争性的MEK1抑制剂，Ki 值为 0.13 nM。它对 A375 细胞中 BRAFV600E 的 EC50值为 7 nM，而对 HCT116 细胞中 KRAS (G13D)的 EC50值为 42 nM。
T74698	RMC-6236 RAS-IN-2
	RMC-6236是一种相关的 RAS（ON）多选择性抑制剂，对CypA蛋白(KD1)的亲和力为55.3 nmol/L，RMC-6236对KRAS突变癌细胞系HPAC (KRASG12D/WT, PDAC)和Capan-2 (KRASG12V/WT, PDAC)， EC50分别为1.2和1.4 nmol/L，可用于癌症治疗。[1,2]
T6878	LJI308	S6 Kinase	MAPK; PI3K/Akt/mTOR signaling
	LJI308 是泛RSK 抑制剂，对 RSK1、RSK2 和 RSK3 的IC50分别为 6、4 和 13 nM。它抑制辐照、EGF 处理和表达 KRAS 突变的细胞中 RSK (T359/S363) 和 YB-1 (S102) 的磷酸化。
T11768	KRAS G12C inhibitor 14	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂（IC50= 18 nM）。
T37130	MRTX1133 formic
	MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells[1][2]. MRTX1133 demonstrates dose-dependent inhibition of the KRAS pathway tumor regression in G12D mutant tumor models[2]. [1]. Xiaolun Wang, et al.Kras g12d inhibitors.WO2021041671A1.[2]. KRAS G12D Inhibitor: MRTX1133. [(accessed on 22 April 2021)];2021 Available onli...
T79057	KRAS G12C inhibitor 58	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 58作为KRAS G12C的抑制剂，专门用于癌症领域的研究应用。
T62566	KRAS G12C inhibitor 53
	KRAS G12C inhibitor 53 (Compound 1) 是一种 KRAS G12C 抑制剂。
T72335	KRAS G12C inhibitor 32	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 32，一种含有八个原子的N杂环化合物，作为KRAS G12C的有效抑制剂。
T64085	KRAS G12C inhibitor 43
	KRAS G12C inhibitor 43 是 KRAS G12C 的有效抑制剂，能够抑制 H358 细胞 (IC50: 0.001-1 μM μM)、 A549 细胞 (IC50>1 μM)、 HCC 细胞 (IC50>1 μM) 的迁移和增殖。
T36676	Rineterkib hydrochloride
	Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer[1]. ERK-IN-1 (compound B) (50, 75 mg/kg, p.o., qd/q2d, 27 days) treatment significantly reduces the tumor volume in the C...
T79799	pan-KRAS-IN-4	Ras	GPCR/G Protein; MAPK
	Pan-KRAS-IN-4 (compound 5) 为一种高效KRAS抑制剂，其IC50值分别为0.37 nM (Kras G12C) 和0.19 nM (Kras G12V)。
T79092	TH-Z827	Ras	GPCR/G Protein; MAPK
	TH-Z827为特异性针对KRAS(G12D)突变的抑制剂，IC50值为2.4 μM。此化合物不与KRAS(WT)或KRAS(G12C)结合，并可抑制KRAS(G12D)与CRAF的相互作用，其IC50值为42 μM。
T74607	KRAS G12D inhibitor 15
	KRAS G12D inhibitor 15 是一种有效的 KRAS G12D 抑制剂。KRAS G12D inhibitor 15 具有研究各种疾病或病症的潜力，例如癌症或癌症转移。
T72599	KRAS inhibitor-11
	KRAS inhibitor-11 是一种 KRAS 抑制剂。
T79148	PROTAC KRAS G12C degrader-3	Ras	GPCR/G Protein; MAPK
	PROTACKRAS G12C degrader-3（Comp 283）是一种癌症研究中使用的高效KRAS G12C降解剂。
T79814	pan-KRAS-IN-3	Ras	GPCR/G Protein; MAPK
	Pan-KRAS-IN-3 (Example 84)为一款pan-KRAS抑制剂，适用于癌症研究领域。
T73864	Deltasonamide 1 TFA
	Deltasonamide 1 TFA 是一种PDE6δ-KRas 抑制剂。Deltasonamide 1 可以抑制 PDE6δ-KRas，KD 为 203 pM。Deltasonamide 1 可用于肿瘤的研究。
T79800	pan-KRAS-IN-2	Ras	GPCR/G Protein; MAPK
	Pan-KRAS-IN-2（compound 6）是一种抑制剂，对KRAS WT及其多种突变体（G12D、G12C、G12V、G12S、G12A、Q61H）表现出极高的抑制活性，其IC50均不超过10 nM；然而对KRAS G13D的抑制活性较低，IC50超过10 μM。
TP2116	SAH-SOS1A
	KRas/son of sevenless 1 (SOS1) interaction inhibitor. Binds within nucleotide binding pocket of KRas (Kd values are 106 - 176 nM for wild type KRas and various KRas mutants). Inhibits nucleotide binding to KRas in a concentration dependent manner. Display
T78651	Glecirasib JAB-21822,KRAS G12C inhibitor 36	Ras	GPCR/G Protein; MAPK
	Glecirasib (KRAS G12C inhibitor 36) 作为潜在的KRAS G12C抑制剂，在Ras蛋白家族中发挥作用，对细胞内信号传递具重要影响，并在生长发育中扮演关键角色。本化合物显示出研究KRAS G12C介导的癌症潜力。
T62751	KRAS inhibitor-12
	KRAS inhibitor-12 (compound 6-1) 是一种 KRAS G12C 的有效抑制剂 (IC50: 0.537 μM)。KRAS inhibitor-12 在 MIA PaCA-2，A549 细胞中表现出 p-ERK 抑制作用，其 IC50 值分别为 1.3，3.7 μM。 KRAS inhibitor-12 具有潜力进行胰腺癌，结直肠癌和肺癌的研究。
T36761	KRAS inhibitor-10
	KRAS inhibitor-10 (WO2021005165 A1, compound 11) is a potent and selective inhibitor of RAS proteins, with a specific focus on KRAS proteins. This orally active anti-cancer agent demonstrates strong efficacy in cancer research, specifically in pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer. KRAS inhibitor-10 is classified as a tetrahydroisoquinoline compound. Its inhibitory properties provide valuable insights and potential therapeutic applications in the field of ...
T79166	KRAS G12C inhibitor 60	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 60 (compound 23)作为一种高效的Kras-G12C抑制剂, 主要应用于肺癌、结直肠癌和胰腺癌的研究领域。
T82352	GADGVGKSAL
	GADGVGKSAL为KRAS G12D突变型10mer肽，具有免疫原性，常用作癌症免疫疗法研究中的新型抗原。
T74663	KRAS G12D inhibitor 17
	KRAS G12D inhibitor 17 (example 8) 是一种喹唑啉连接 (4R)-4-羟基-l -脯氨酸酰胺化合物，可诱导 G12D 突变 KRAS 蛋白降解。KRAS G12D inhibitor 17 是一种 PTOTAC。
T72336	KRAS G12C inhibitor 45
	KRAS G12C inhibitor 45 是一种有效的KRAS G12C 抑制剂。
T82349	GAGGVGKSA
	GAGGVGKSA，作为wild-type KRAS G12D 9mer肽，具有免疫原性，可用于研究癌症免疫疗法中新抗原的应用。
T79870	RMC-4998	Ras	GPCR/G Protein; MAPK
	RMC-4998是一种分子胶化合物，显示出显著的抗肿瘤活性。该化合物能够与CYPA形成三元复合体，进而与KRAS G12C的激活状态突变体相结合。RMC-4998与CYPA结合后，可阻碍激活的KRAS G12C突变体与其下游效应蛋白的交互作用，有效抑制了促细胞增殖的信号传导。
T79673	LUNA18	Ras	GPCR/G Protein; MAPK
	LUNA18作为口服活性KRAS抑制剂，其对KRASG12D-SOS的IC50值<2 nM，适用于癌症研究。

化合物

KRas G12C inhibitor 1

Cat.No: T11776

Target: Ras

KRAS G12D inhibitor 1

Cat.No: T9674

KRAS mutant protein inhibitor 1

Cat.No: T40272

Cat.No: T8418

Target: Others

Cat.No: T11224

Synonym: ERK-IN-1

Target: ERK, Raf

KRAS G12C mutant protein inhibitor A-1

Cat.No: T77805

Cat.No: T15735

Synonym: CI 940,LMB,来普霉素B

Target: CRM1, Antibiotic, Antifungal

PROTAC K-Ras Degrader-1

Cat.No: T13844

Target: Ras

Cat.No: T9533

Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide

Target: Others

K-Ras ligand-Linker Conjugate 1

Cat.No: T18054

Target: Others

KRAS degrader-1

Cat.No: T79147

K-Ras G12C-IN-1

Cat.No: T11735

Target: Phosphatase

SOS1/KRAS-IN-1

Cat.No: T79162

Target: Ras

KRAS G12D modulator-1

Cat.No: T79072

Target: Ras

KRas G12R inhibitor 1

Cat.No: T74973

PROTAC KRAS G12C degrader-1

Cat.No: T77926

Target: PROTACs

Cat.No: T11282

Target: Transferase

Cat.No: T12979

Target: p38 MAPK, MAPK, Ras

Kras4B G12D-IN-1

Cat.No: T78170

Target: Ras

Cat.No: T81263

Target: Ras

Cat.No: T7123

Target: VEGFR, p38 MAPK, JAK, Src

Cat.No: T6843

Synonym: G-868,GDC0623,RG 7421,MEK inhibitor 1

Target: Apoptosis, MEK

Cat.No: T74698

Synonym: RAS-IN-2

Cat.No: T6878

Target: S6 Kinase

KRAS G12C inhibitor 14

Cat.No: T11768

Target: Ras

MRTX1133 formic

Cat.No: T37130

KRAS G12C inhibitor 58

Cat.No: T79057

Target: Ras

KRAS G12C inhibitor 53

Cat.No: T62566

KRAS G12C inhibitor 32

Cat.No: T72335

Target: Ras

KRAS G12C inhibitor 43

Cat.No: T64085

Rineterkib hydrochloride

Cat.No: T36676

pan-KRAS-IN-4

Cat.No: T79799

Target: Ras

Cat.No: T79092

Target: Ras

KRAS G12D inhibitor 15

Cat.No: T74607

KRAS inhibitor-11

Cat.No: T72599

PROTAC KRAS G12C degrader-3

Cat.No: T79148

Target: Ras

pan-KRAS-IN-3

Cat.No: T79814

Target: Ras

Deltasonamide 1 TFA

Cat.No: T73864

pan-KRAS-IN-2

Cat.No: T79800

Target: Ras

Cat.No: TP2116

Cat.No: T78651

Synonym: JAB-21822,KRAS G12C inhibitor 36

Target: Ras

KRAS inhibitor-12

Cat.No: T62751

KRAS inhibitor-10

Cat.No: T36761

KRAS G12C inhibitor 60

Cat.No: T79166

Target: Ras

Cat.No: T82352

KRAS G12D inhibitor 17

Cat.No: T74663

KRAS G12C inhibitor 45

Cat.No: T72336

Cat.No: T82349

Cat.No: T79870

Target: Ras

Cat.No: T79673

Target: Ras

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His) NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2B,K-RAS,Kirsten...	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His) KRAS1,K-RAS4B,Kirsten rat sarcoma viral on...	Human	E. coli
	KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His) KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His) Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...	Human	E. coli
	KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-06138	KRAS Protein, Human, Recombinant (61Q, His) Kirsten rat sarcoma viral oncogene homolog,K-RAS2B,NS3,K-RAS...	Human	E. coli
	KRAS Protein, Human, Recombinant (61Q, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21.9 kDa and the accession number is P01116-2.
TMPU-00001	KRAS Protein, Human, Recombinant (G12S, GST) NS,C-K-RAS,K-RAS2A,KRAS1,K-RAS2B,KRAS<...	Human	E. coli
	KRAS Protein, Human, Recombinant (G12S, GST) is expressed in E. coli expression system with GST tag. The accession number is P01116.
TMPY-06345	KRAS Protein, Human, Recombinant (His & Avi), Biotinylated RASK2,K-RAS2A,RALD,C-K-RAS,NS3,Kirsten rat sarcoma viral onc...	Human	E. coli
	KRAS Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with His and Avi tag. The predicted molecular weight is 23.78 kDa and the accession number is P01116-2.
TMPY-03487	NRAS Protein, Human, Recombinant (His) NS6,NCMS,CMNS,neuroblastoma RAS viral (v-ras) oncogene homol...	Human	E. coli
	NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL6, a promyelocytic leukemia line. The mammalian ras gene family consists of the Harvey and Kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1), and the N-ras gene. They differ significantly only in the C-terminal 4 amino acids...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-02245	SNAP-25 Protein, Human, Recombinant (His) synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ	Human	E. coli
	Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPK-00383	ACE2/ACEH Protein, Human, Recombinant (His & Avi) ACE2,ACE-2,ACEH	Human	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) RSPO,CRISTIN3,R-spondin 1	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His) W282,W264,CEA,CD66D,CGM1,MGC11987...	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-01938	CD98 Protein, Human, Recombinant (His) 4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...	Human	HEK293 Cells
	CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 r...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His) ActRIIB,activin A receptor, type IIB,4930516B21...	Mouse	HEK293 Cells
	ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His) NR4,interleukin 13 receptor, alpha 1,CD2	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor sup...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-04346	PD-L2 Protein, Human, Recombinant (His) PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-02525	RGMA Protein, Human, Recombinant (His) repulsive guidance molecule family member a,RGM	Human	HEK293 Cells
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-00861	IL-33 Protein, Human, Recombinant IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...	Human	E. coli
	IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His) FLK2,FLK-2,CD135,STK1,fms-related tyrosine...	Human	HEK293 Cells
	FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01185	DR5/TRAIL R2 Protein, Human, Recombinant (His) KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His) thymic stromal lymphopoietin	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06418	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) R-spondin 2,CRISTIN2	Human	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-03290	HGF Protein, Mouse, Recombinant hepatocyte growth factor (hepapoietin A,NK1,scatter...	Mouse	HEK293 Cells
	HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His) erb-b2 receptor tyrosine kinase 4	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL	Human	E. coli
	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01883	EPOR Protein, Human, Recombinant (His) erythropoietin receptor,EPO-R	Human	HEK293 Cells
	EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc) WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...	Human	HEK293 Cells
	TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3,CD223	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His) ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-00947	VCAM-1 Protein, Human, Recombinant (hFc) INCAM-100,CD106,VCAM-1,vascular c...	Human	HEK293 Cells
	VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-04165	FGFR3 Protein, Human, Recombinant (His) JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-01137	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His) HHF5,CD220,insulin receptor	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-02033	CD44 Protein, Human, Recombinant (His) CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...	Human	HEK293 Cells
	CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-01744	ACVR2A Protein, Human, Recombinant (His) activin A receptor, type IIA,ACVR2,ACTRII	Human	HEK293 Cells
	ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His) BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-01851	CD73 Protein, Human, Recombinant (His) eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...	Human	HEK293 Cells
	CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-01949	CD19 Protein, Human, Recombinant (His) CD19 molecule,B4,CVID3	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-00978	Progranulin Protein, Human, Recombinant (His) PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...	Human	HEK293 Cells
	Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-05208	PD-L1 Protein, Human, Recombinant CD274 molecule,PDCD1L1,PD-L1,PDL<...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03407	NQO1 Protein, Human, Recombinant (His) NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagoni...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01862	IL-4 Protein, Human, Recombinant Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF	Human	E. coli
	IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
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重组蛋白

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

Cat.No: TMPY-04116

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12D, His)

Cat.No: TMPY-06056

Species: Human

Expression System: E. coli

KRAS Protein,Human, Recombinant (Q61H, His)

Cat.No: TMPY-01888

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Cat.No: TMPY-04113

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (61Q, His)

Cat.No: TMPY-06138

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12S, GST)

Cat.No: TMPU-00001

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06345

Species: Human

Expression System: E. coli

NRAS Protein, Human, Recombinant (His)

Cat.No: TMPY-03487

Species: Human

Expression System: E. coli

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03745

Species: Human

Expression System: HEK293 Cells

SNAP-25 Protein, Human, Recombinant (His)

Cat.No: TMPY-02245

Species: Human

Expression System: E. coli

ACE2/ACEH Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00383

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01147

Species: Human

Expression System: HEK293 Cells

CEACAM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01850

Species: Human

Expression System: HEK293 Cells

CD98 Protein, Human, Recombinant (His)

Cat.No: TMPY-01938

Species: Human

Expression System: HEK293 Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

ACVR2B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01281

Species: Mouse

Expression System: HEK293 Cells

IL-13RA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01258

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04346

Species: Human

Expression System: HEK293 Cells

RGMA Protein, Human, Recombinant (His)

Cat.No: TMPY-02525

Species: Human

Expression System: HEK293 Cells

IL-33 Protein, Human, Recombinant

Cat.No: TMPY-00861

Species: Human

Expression System: E. coli

FLT3 Protein, Human, Recombinant (T227M, His)

Cat.No: TMPY-01247

Species: Human

Expression System: HEK293 Cells

DR5/TRAIL R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01185

Species: Human

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130S, His)

Cat.No: TMPY-05220

Species: Human

Expression System: HEK293 Cells

R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06418

Species: Human

Expression System: HEK293 Cells

HGF Protein, Mouse, Recombinant

Cat.No: TMPY-03290

Species: Mouse

Expression System: HEK293 Cells

ErbB4 Protein, Human, Rhesus, Recombinant (His)

Cat.No: TMPY-02813

Species: Human,Rhesus

Expression System: HEK293 Cells

FLT3 Ligand Protein, Human, Recombinant

Cat.No: TMPY-06873

Species: Human

Expression System: E. coli

EPOR Protein, Human, Recombinant (His)

Cat.No: TMPY-01883

Species: Human

Expression System: HEK293 Cells

TIGIT Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04970

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04348

Species: Human

Expression System: HEK293 Cells

VCAM-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00947

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04165

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

Cat.No: TMPY-01137

Species: Human

Expression System: HEK293 Cells

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

Cat.No: TMPY-01146

Species: Human

Expression System: HEK293 Cells

CD44 Protein, Human, Recombinant (His)

Cat.No: TMPY-02033

Species: Human

Expression System: HEK293 Cells

ACVR2A Protein, Human, Recombinant (His)

Cat.No: TMPY-01744

Species: Human

Expression System: HEK293 Cells

BTN3A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03967

Species: Human

Expression System: HEK293 Cells

CD73 Protein, Human, Recombinant (His)

Cat.No: TMPY-01851

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (His)

Cat.No: TMPY-01949

Species: Human

Expression System: HEK293 Cells

Progranulin Protein, Human, Recombinant (His)

Cat.No: TMPY-00978

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant

Cat.No: TMPY-05208

Species: Human

Expression System: HEK293 Cells

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

NQO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03407

Species: Human

Expression System: E. coli

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

IL-4 Protein, Human, Recombinant

Cat.No: TMPY-01862

Species: Human

Expression System: E. coli

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