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Search Results for " cip2a "
Targets Recommended: Apoptosis Phosphatase Akt

3

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T35528 TD52

Apoptosis; Phosphatase; Akt Apoptosis; Cytoskeletal Signaling; Metabolism; PI3K/Akt/mTOR signaling
TD52 是 PP2A (CIP2A) 癌性抑制剂的口服活性抑制剂。 TD52 是厄洛替尼衍生物,通过干扰 Elk1 与 CIP2A 启动子的结合间接降低了 CIP2A
T35528L TD52 dihydrochloride

TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl

Others Others
TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signaling pathway, resulting in the induction of apoptosis in triple-negative breast cancer (TNBC) cells. Mechanistically, TD52 dihydrochloride disrupts the binding of Elk1 to the CIP2A promoter, effectively reducing CIP2A levels. Notably, TD52 dihydrochloride demonstrates powerful anti...
T63259 PP2A Cancerous-IN-1

Others Others
PP2A Cancerous-IN-1 是强效的 CIP2A(Cancerous inhibitor of PP2A) 和 p-Akt 抑制剂,表现出强大的抗增殖作用。

化合物

TD52
Cat.No: T35528
Synonym:
Target: Apoptosis, Phosphatase, Akt
TD52 dihydrochloride
Cat.No: T35528L
Synonym: TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl
Target: Others
PP2A Cancerous-IN-1
Cat.No: T63259
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN1305 Ethoxysanguinarine

乙氧基血根碱,6-Ethoxydihydrosanguinarine

Apoptosis; AChR Apoptosis; Neuroscience
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) 是存在于龙葵中的一种苯并菲啶生物碱天然产物,通过抑制蛋白磷酸酶 2A,可抑制结直肠癌细胞活力,诱导细胞凋亡。

天然产物

Ethoxysanguinarine
Cat.No: TN1305
Synonym: 乙氧基血根碱,6-Ethoxydihydrosanguinarine
Target: Apoptosis, AChR
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