Anticancer agent 32

Anticancer agent 32 (compound 2g) 是一种抗癌剂。Anticancer agent 32 能够影响细胞周期并诱导细胞凋亡，表现出抗癌效果。Anticancer agent 32 能够用于研究癌症。

Antiproliferative agent-60 (compound 8c)，一种11-Azaartemisinin的衍生物，具备出色的抗癌特性。该化合物在各种癌细胞系—表皮样癌(KB)、HepG2和A549—中的IC50值依次为7.7 μM、42.5 μM和15.5 μM。此外，Antiproliferative agent-60对肿瘤细胞具有显著的选择性，其对比于Hek293正常细胞的选择性高达32倍。

Antimicrobial agent-32 (Compound 4g) 是一种抗菌剂，对多种细菌包括Staphylococcus aureus、Bacillus subtilis、和Bacillus cereus表现出显著的活性(MIC=1000 µg/mL)，并对Klebsiella pneumonia和Staphylococcus aureus (MRSA)的活性更强(MIC=500 µg/mL)，而对Escherichia coli的MIC为250 µg/mL。此外，Antimicrobial agent-32 还能抑制MCF-7、HCT-116和HepG-2细胞的增殖，具有抗癌活性。

MYF-03-176 is an orally active TEAD1/3/4 inhibitor with IC₅₀ values of 47/32/71 nM, respectively. It also inhibits TEAD transcriptional activity and cell growth in NCI-H226 cells, exhibiting antitumour activity in malignant pleural mesothelioma (MPM) cells with defective Hippo signalling and in mouse xenograft models.