4-aminopyridine

4-Aminopyridine（Dalfampridine）是一种非选择性钾（K+）通道阻断剂，作用于细胞膜的细胞质侧。

3-Hydroxy-4-aminopyridine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T66009，CAS号为 52334-53-9。

Heterocyclic compound-pyridine, intermediate and building block-nucleophile

GYKI 52466 is an allosteric AMPA receptor antagonist. It selectively inhibits AMPA-induced inward currents (IC50 = 7.5 µM) over NMDA- or GABA-induced inward currents in primary rat hippocampal neurons at 50 µM but also inhibits kainate-induced inward currents in the same cells (IC50 = 11 µM).2 GYKI 52466 (10 µM) reduces the amplitude of spontaneous excitatory postsynaptic currents (EPSCs) in the same cells. It increases the latency to seizure onset and reduces mortality in a rat model of generalized tonic-clonic seizures induced by 4-aminopyridine (4-AP) when administered at doses of 25 and 50 mg kg. GYKI 52466 (30 mg kg) prevents neuronal damage in the CA1 region of the hippocampus in a rat model of global ischemia-reperfusion injury induced by four-vessel occlusion.

2,4-Dichloro-3-nitro-4-(N-ethoxycarbonyl)aminopyridine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU0895，CAS号为 947146-17-0。

Methyl 3-aminopyridine-4-carboxylate 是一种高纯度生化试剂，适合作为生物材料或有机合成中间体，广泛应用于生命科学领域的研究与实验。