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72

抑制剂 & 化合物

17

天然产物

77

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T37819 Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept...
T37595 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.
T50025 Lonazolac

PPAR DNA Damage/DNA Repair; Metabolism
Lonazolac 是一种具有抗炎特性的非甾体抗风湿剂。
T21572 Erythromycin A enol ether

Others Others
Erythromycin A enol ether 是大环内酯类抗生素红霉素A 的降解产物。
T0668 1-Aminohydantoin hydrochloride

Others Others
1-Aminohydantoin hydrochloride 是一种呋喃妥因在动物组织中的主要代谢物。它与组织蛋白共价结合,在微酸性条件下从组织中释放出来,与 2-硝基苯甲醛衍生形成 AHD 的硝基苯基衍生物可被检测。它可作为测定肉、奶等兽药残留的测定指标。
T37885 1-Dodecylimidazole

Antifungal Microbiology/Virology
1-Dodecylimidazole 是溶酶体活性洗涤剂。1-Dodecylimidazole 通过在溶酶体中的酸依赖性积累、溶酶体膜的破坏和半胱氨酸蛋白酶释放到细胞质中而导致细胞死亡。它显示出降胆固醇和广谱抗真菌活性。
T0312 Toluidine Blue

氯托洛宁,Blutene chloride

Others Others
Toluidine Blue (Blutene chloride) 是碱性噻嗪异染染料,能够高度亲和酸性组织成分,广泛应用于活体组织的重要染色及特殊染色。
T23173 Ponceau S

丽春红 S,Acid Red 112,Ponceau S Staining Solution

Others Others
Ponceau S (Ponceau S Staining Solution) 是一种常见的、用于 Western blot 的染色剂。它以酸性水溶液形式使用,能够与抗体-抗原结合兼容,将膜上的蛋白质染成红色。
T20362 Glutamyl-glutamic acid

Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid

Amino Acids and Derivatives Metabolism
Glutamyl-glutamic acid (Glu-glu) 是一些微球菌和节杆菌属菌的胞壁中的肽桥。
T19139 4-Nitrophenyl α-D-galactopyranoside

PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal

Others Others
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) 是 4-硝基苯基 (pNP) 糖吡喃糖苷的人工底物,可用于 α-半乳糖苷酶活性的检测。它用作底物能够显著增加 pNP 的释放量。
T19764 Trepibutone

AA-149,Colibil, Supacal,AA149,AA 149,曲匹布通

Others Others
Trepibutone (AA-149) 是一种酸性药物,具有不依赖于 pH 值的释放能力。
T4968 KHS 101

Microtubule Associated Cytoskeletal Signaling
KHS 101 是一种新型转化酸性卷曲螺旋蛋白 3 (TACC3) 的抑制剂。它是神经元分化的选择性诱导剂。
T11090L1 Aldoxorubicin hydrochloride

Aldoxorubicin hydrochloride (1361644-26-9 Free base)

Topoisomerase DNA Damage/DNA Repair
Aldoxorubicin hydrochloride 是 Doxorubicin (DNA 拓扑异构酶 II 抑制剂) 的白蛋白结合前药。Aldoxorubicin hydrochloride 在酸性条件下从白蛋白中释放出来。 Aldoxorubicin hydrochloride 显示出有效的抗肿瘤活性。
T40863 Bisdionin C

Antibacterial Microbiology/Virology
Bisdionin C 是一种有效的 GH18 chitinase 抑制剂,对 A. fumigatus ChiB1 的 IC50 为 0.2 μM。 Bisdionin C 抑制人巨噬细胞壳三糖苷酶 (HCHT, IC50 = 8.3 μM) 和酸性哺乳动物几丁质酶 (AMCase, IC50 = 3.4 μM)。
T9592 OATD-01

Others Others
OATD-01 是一种壳三糖苷酶及酸性哺乳动物几丁质酶的高活性抑制剂,对CHIT1具有低纳摩尔活性 (hCHIT1,IC50=23 nM)。它在多个物种中显示出良好的药代动力学特征,在体内具有显著的抗纤维化活性,可用于研究肺纤维化。
T8492 BO-264

Apoptosis; FGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
BO-264 是一种有口服活性的转化酸性卷曲螺旋 3 抑制剂,可特异性阻断 FGFR3-TACC3融合蛋白的功能。它诱导纺锤体检查点依赖的有丝分裂阻滞,DNA 损伤和细胞凋亡,具有广谱抗肿瘤活性。
T23280 Ruthenium Red

钌红,Ammoniated ruthenium oxychloride

Calcium Channel Membrane transporter/Ion channel; Metabolism
Ruthenium Red (Ammoniated ruthenium oxychloride) 是一种 L 型钙电流 (ICa) 阻断剂,是一种聚阳离子染料,广泛用于电子显微镜 (EM) 下细胞、组织和营养细菌的观察。它能与磷脂和脂肪酸反应强烈,并与酸性粘多糖结合。
TP2325L Endotoxin Inhibitor acetate(147396-10-9 free base)

Others Others
Endotoxin Inhibitor acetate(147396-10-9 free base) 对细菌生理活性有很强的阻断作用,从而产生具有二硫键和大量赖氨酸的抗菌毒素抑制剂序列。内毒素抑制剂醋酸盐在酸性条件下更可能发挥生理活性
T1756 Ilaprazole sodium

IY-81149 sodium,艾普拉唑钠

Proton pump; TOPK MAPK; Membrane transporter/Ion channel
Ilaprazole sodium (IY-81149 sodium) 是一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制 H+/K+-ATPase,在兔壁细胞制剂中的 IC50为 6 μM。它也是一种有效的 T 细胞起源蛋白激酶(TOPK)抑制剂,用于胃溃疡的研究。
T6929 Pantoprazole sodium

Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc

Apoptosis; Others; Proton pump; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others
Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂,是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,IC50为 6.8 μM。它可以改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
TF0106 Cholesteryl Hemisuccinate Tris Salt

Apoptosis Apoptosis
Cholesteryl Hemisuccinate Tris Salt 是一种具有保肝和抗癌活性的酸性胆固醇酯,是一种含有柴胡皂苷-d的二棕榈酰磷脂酰胆碱脂质体中的膜稳定剂,可增强顺铂的抗癌功效。Cholesteryl hemisuccinate 具有抗肿瘤活性,抑制肿瘤生长,抑制对乙酰氨基酚 (AAP) 的肝毒性,预防 AAP 诱导的肝细胞凋亡。Cholesteryl hemisuccinate 可保护啮齿动物免受对乙酰氨基酚、阿霉素、四氯化碳、氯仿和半乳糖胺的毒性作用。
T70177 OAT-177

OAT-177 is a potent, selective, orally active acidic mammalian chitinase (AMCase) inhibitor.
T38850 AZD4721

RIST4721,AZD4721

AZD4721 (RIST4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 ( CXCR2 ). AZD4721 has the potential for the research of inflammatory disease.
T27187 DK-1-49

DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.
T16272 Naproxen etemesil

LT-NS 001,MX 1094

PDE Metabolism
Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.
T32293 JK-2 lithium

JK-2,JK2,JK 2

JK-2 is a hydrogen sulfide (H2S) donor. At acidic pH, it shows a greatly accelerated H2S release upon protonation-induced intramolecular cyclization.
T11289 Finafloxacin

Others Others
Finafloxacin, a fluoroquinolone antimicrobial agent from a new 8-cyano subclass, is most effective in slightly acidic environments (pH 5.0-6.0), a condition where other fluoroquinolones typically reduce in activity. It selectively targets bacterial type II topoisomerases, such as DNA gyrase and DNA topoisomerase IV, making it suitable for treating serious bacterial infections particularly in acidic contexts, including urinary tract infections (UTIs) and Helicobacter pylori infections.
T24970 1'-Ethylascorbigen

1'-Ethylascorbigen releases ascorbic acid in acidic solution results in an increase in the cells' ability to produce PGE2 & LTB4. It has been shown to inhibit the growth of experimental murine tumors.
T68890 Desvaleryl Valsartan

Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan. It is a degradation product formed under acidic conditions.
T32287 Jegosapogenol A

Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Barringtogenol C exists in tea. It can
T78621 Finafloxacin hydrochloride

Finafloxacin为一种氟喹诺酮类抗微生物剂,其抗菌活性在微酸性环境下最为显著。
T20098 NH2-PEG3-C2-Boc

Amino-PEG3-t-butyl ester

Amino-PEG3-t-butyl ester is a PEG derivative containing an amino group with the t-butyl protected carboxyl group. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
T25283 Cytochrome P450 2C9

Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase

Cytochrome P450 2C9 is a cytochrome P-450 subtype that possesses specificity for acidic xenobiotics. It oxidizes a wide range of important clinical drugs under the categories of nonsteroidal anti-inflammatory agents, anticoagulants, hypoglycemic agents, a
T38645 Acetyl-Hirudin (54-65) (sulfated)

Acetyl-Hirudin (54-65) (sulfated) directly binds to thrombin-rHCII(L444R) and hinders the interaction between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin, which stabilizes the complex.
T36721 Dehydro Amlodipine (fumarate)

Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine. It is a degradation product formed during storage or when amlodipine is subjected to oxidative or acidic conditions or undergoes photo or electrochemical degradation.
T20915 Azido-PEG2-t-butyl ester

Azido-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.
T76471 Lactoferricin, bovine

Lactoferricin, bovine 是一种铁结合糖蛋白,来源于牛乳铁蛋白的酸性水解。Lactoferricin, bovine 具有杀菌、抗真菌、抗寄生虫、抗肿瘤、抗病毒和免疫调节活性。
T76238 Zilganersen

Zilganersen (ION373) 为GFAP抑制剂,属于反义寡核苷酸类。适用于亚历山大病(AxD)的研究。
T81811 Methyl yellow

Dimethyl yellow,Solvent Yellow 2

Methyl yellow(Solvent Yellow 2)为pH指示剂,该化合物在pH低于4.0时显红色,高于4.0时转为黄色。
T20860 Hydroxy-PEG12-t-butyl ester

Hydroxy-PEG12-t-butyl ester is a PEG derivative containing a hydroxyl group and a t-butyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Under acidic conditions, the t-butyl protected carbox
T72450 Influenza virus-IN-6

Influenza Virus Microbiology/Virology
Influenza virus-IN-6 (Compound 35) 是一种针对流感病毒聚合酶酸性蛋白亚基内切酶N端结构域(PAN)的高效抑制剂,展现出0.20 μM的IC50值。
T71872 Boc-8-aoc-oh

Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T70303 N-Boc-15-aminopentadecanoic acid

N-Boc-15-aminopentadecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T76168 Carboxypeptidase C

CarboxypeptidaseC为生化研究中常用的羧肽酶,专门用于切除多肽链羧基末端的赖氨酸、精氨酸和脯氨酸,同时也能处理包含中性、脂肪族、芳香族及酸性蛋白质氨基酸的肽链。
T80870 VE-PTP-IN-1

VE-PTP-IN-1 (compound 2) 为一种选择性VE-PTP抑制剂,呈弱酸性,涉及调控血管稳态及血管生成。
T39855 LysoTracker Red

LysoTracker Red DND-99

LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other standard assays (Annexin, terminal dUTP nick end labeling, Nile blue sulfate, neutral red, and acridine orange). LysoTracker Red is a marker for late endosomes and lysosomes.
T68842 Complestatin

Complestatin is a compound extracted from Streptomyces lavendulae mycelia; on acid hydrolysis yields D-4-hydroxyphenylglycine & D-3,5-dichloro-4-hydroxyphenylglycine & acidic chromophore; inhibits gp120-CD4 binding. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. It has a role as a metabolite, an antimicrobial agent and an anti-HIV-1 agent.
T63934 PAK4-IN-1

PAK4-IN-1 是一个选择性的、有效的、口服具有活力的 PAK4 抑制剂,在酸性和中性条件下都很稳定。PAK4-IN-1 在体内表现出良好的抗肿瘤作用。
T71906 Boc-12-Ado-OH

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T80427 Jingzhaotoxin-II

Sodium Channel Membrane transporter/Ion channel
Jingzhaotoxin-II是由32个氨基酸组成的神经毒素,包括两个酸性残基和两个碱性残基。该毒素能够抑制电压门控钠通道(VGSC),并在心肌细胞上明显减缓TTX抗性(TTX-R) VGSC的快速失活,其IC50值为0.26μM。

化合物

Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
Cat.No: T37819
Synonym:
Target:
Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
Cat.No: T37595
Synonym:
Target:
Lonazolac
Cat.No: T50025
Synonym:
Target: PPAR
Erythromycin A enol ether
Cat.No: T21572
Synonym:
Target: Others
1-Aminohydantoin hydrochloride
Cat.No: T0668
Synonym:
Target: Others
1-Dodecylimidazole
Cat.No: T37885
Synonym:
Target: Antifungal
Toluidine Blue
Cat.No: T0312
Synonym: 氯托洛宁,Blutene chloride
Target: Others
Ponceau S
Cat.No: T23173
Synonym: 丽春红 S,Acid Red 112,Ponceau S Staining Solution
Target: Others
Glutamyl-glutamic acid
Cat.No: T20362
Synonym: Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid
Target: Amino Acids and Derivatives
4-Nitrophenyl α-D-galactopyranoside
Cat.No: T19139
Synonym: PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal
Target: Others
Trepibutone
Cat.No: T19764
Synonym: AA-149,Colibil, Supacal,AA149,AA 149,曲匹布通
Target: Others
KHS 101
Cat.No: T4968
Synonym:
Target: Microtubule Associated
Aldoxorubicin hydrochloride
Cat.No: T11090L1
Synonym: Aldoxorubicin hydrochloride (1361644-26-9 Free base)
Target: Topoisomerase
Bisdionin C
Cat.No: T40863
Synonym:
Target: Antibacterial
OATD-01
Cat.No: T9592
Synonym:
Target: Others
BO-264
Cat.No: T8492
Synonym:
Target: Apoptosis, FGFR
Ruthenium Red
Cat.No: T23280
Synonym: 钌红,Ammoniated ruthenium oxychloride
Target: Calcium Channel
Endotoxin Inhibitor acetate(147396-10-9 free base)
Cat.No: TP2325L
Synonym:
Target: Others
Ilaprazole sodium
Cat.No: T1756
Synonym: IY-81149 sodium,艾普拉唑钠
Target: Proton pump, TOPK
Pantoprazole sodium
Cat.No: T6929
Synonym: Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc
Target: Apoptosis, Others, Proton pump, HIF, Autophagy
Cholesteryl Hemisuccinate Tris Salt
Cat.No: TF0106
Synonym:
Target: Apoptosis
OAT-177
Cat.No: T70177
Synonym:
Target:
AZD4721
Cat.No: T38850
Synonym: RIST4721,AZD4721
Target:
DK-1-49
Cat.No: T27187
Synonym:
Target:
Naproxen etemesil
Cat.No: T16272
Synonym: LT-NS 001,MX 1094
Target: PDE
JK-2 lithium
Cat.No: T32293
Synonym: JK-2,JK2,JK 2
Target:
Finafloxacin
Cat.No: T11289
Synonym:
Target: Others
1'-Ethylascorbigen
Cat.No: T24970
Synonym:
Target:
Desvaleryl Valsartan
Cat.No: T68890
Synonym:
Target:
Jegosapogenol A
Cat.No: T32287
Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D
Target:
Finafloxacin hydrochloride
Cat.No: T78621
Synonym:
Target:
NH2-PEG3-C2-Boc
Cat.No: T20098
Synonym: Amino-PEG3-t-butyl ester
Target:
Cytochrome P450 2C9
Cat.No: T25283
Synonym: Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase
Target:
Acetyl-Hirudin (54-65) (sulfated)
Cat.No: T38645
Synonym:
Target:
Dehydro Amlodipine (fumarate)
Cat.No: T36721
Synonym:
Target:
Azido-PEG2-t-butyl ester
Cat.No: T20915
Synonym:
Target:
Lactoferricin, bovine
Cat.No: T76471
Synonym:
Target:
Zilganersen
Cat.No: T76238
Synonym:
Target:
Methyl yellow
Cat.No: T81811
Synonym: Dimethyl yellow,Solvent Yellow 2
Target:
Hydroxy-PEG12-t-butyl ester
Cat.No: T20860
Synonym:
Target:
Influenza virus-IN-6
Cat.No: T72450
Synonym:
Target: Influenza Virus
Boc-8-aoc-oh
Cat.No: T71872
Synonym:
Target:
N-Boc-15-aminopentadecanoic acid
Cat.No: T70303
Synonym:
Target:
Carboxypeptidase C
Cat.No: T76168
Synonym:
Target:
VE-PTP-IN-1
Cat.No: T80870
Synonym:
Target:
LysoTracker Red
Cat.No: T39855
Synonym: LysoTracker Red DND-99
Target:
Complestatin
Cat.No: T68842
Synonym:
Target:
PAK4-IN-1
Cat.No: T63934
Synonym:
Target:
Boc-12-Ado-OH
Cat.No: T71906
Synonym:
Target:
Jingzhaotoxin-II
Cat.No: T80427
Synonym:
Target: Sodium Channel
Cat. No. Product Name Target Signaling Pathways
T18930 Bromothymol Blue

Others Others
Bromothymol Blue 是 pH 指示剂,在测定弱酸弱碱时使用,在酸性条件下为黄色,在碱性条件下为蓝色。
T0019 Betaine chloride

Betaine hydrochloride,盐酸甜菜碱

Others; Chloride channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism; Others
Betaine chloride (Betaine hydrochloride) 是一种天然化合物,在许多食物中能够发现,也是能够维持正常 DNA 甲基化模式的特性甲基供体。
TN6699 DL-Malic acid

E 296,Hydroxybutanedioic acid

Endogenous Metabolite Metabolism
DL-Malic acid (Hydroxybutanedioic acid) 是一种存在于水果如苹果和梨中二羧酸。 它在许多酸味或酸味食物中起作用。
T5263 p-Hydroxymandelic acid

4-羟基扁桃酸,4-Hydroxymandelic acid

Others; Endogenous Metabolite Metabolism; Others
p-Hydroxymandelic acid (4-Hydroxymandelic acid) 是有价值的芳香类化学品,常用于生产药物和食品添加剂。
T4784 (S)-(-)-Phenylethanol

(S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol

Others; Endogenous Metabolite Metabolism; Others
(S)-(-)-Phenylethanol ((-)-Methyl phenyl carbinol) 是内源性代谢产物的一种。
T5082 Calcium 2-hydroxy-4-(methylthio)butanoate

羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt

Others; Endogenous Metabolite Metabolism; Others
Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) 是内源性代谢产物的一种。
T2834 Nobiletin

Hexamethoxyflavone,川陈皮素,川皮苷

Apoptosis; MMP; Reactive Oxygen Species; ROR; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
Nobiletin (Hexamethoxyflavone) 是一种来自柑橘皮的聚甲氧基黄酮,是RORs 激动剂,可改善记忆力丧失。它可降低分化的 C2C12 肌管中的ROS 水平,并具有抗炎,抗癌,抗血管生成,抗增殖,抗转移和诱导细胞凋亡作用。
Fr13883 3-Methoxyphenylacetic acid

Others Others
3-Methoxyphenylacetic acid 是 m-hydroxyphenylacetic (m-OHPAA) 的衍生物,茄形假丝酵母中的一种植物毒素。它可用于针对介氧菌根腐烂的毒素介导的生物测定法的开发。
T4773 3-Ethoxy-3-oxopropanoic acid

Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯

Others; Endogenous Metabolite Metabolism; Others
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) 是内源性代谢产物的一种。
T2818 Methyl Vanillate

Reactive Oxygen Species; Wnt/beta-catenin; Endogenous Metabolite Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
Methyl vanillate 是一种枳椇属植物中的提取物,是Wnt/β-catenin 信号通路活化剂,是一种香草酸的甲酯。它具有抗氧化作用。
T4798 N-Acetyl-L-leucine

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-leucine 是内源性代谢产物的一种。
T4768 Diethyl oxalpropionate

草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE

Others; Endogenous Metabolite Metabolism; Others
Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。
T4837 Itaconic acid

methylene-butanedioicaci,衣康酸

Others; Endogenous Metabolite Metabolism; Others
Itaconic acid (methylene-butanedioicaci) 是聚合物,化学物质和燃料的合成前体。Itaconic acid 可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。
T7814L Alloxan

NSC 7169,NSC7169,NSC-7169

Alloxan is an acidic compound formed by the oxidation of URIC ACID.
T32740 Libramycin A

Libramycin A is a fat-soluble, weakly acidic substance extracted from Streptomyces.
T32329 Juzirine

Juzirine is a member of the class of benzylisoquinolines. Benzylisoquinolines are organic compounds containing an isoquinoline to which a benzyl group is attached. Juzirine, practically insoluble (in water), is a very weakly acidic compound (based on its
T73068 Mammea A/BA

Mammea A/BA 对克氏锥虫 (T. cruzi) 显示出有效抗性。通过诱导线粒体功能障碍、产生活性氧 (ROS)、DNA 片段化以及增加酸性液泡数量,Mammea A/BA 触发细胞死亡机制,包括细胞凋亡 (apoptosis)、细胞自噬 (autophagy) 和细胞坏死,对于南美锥虫病的研究具有潜在应用价值。

天然产物

Bromothymol Blue
Cat.No: T18930
Synonym:
Target: Others
Betaine chloride
Cat.No: T0019
Synonym: Betaine hydrochloride,盐酸甜菜碱
Target: Others, Chloride channel, Endogenous Metabolite
DL-Malic acid
Cat.No: TN6699
Synonym: E 296,Hydroxybutanedioic acid
Target: Endogenous Metabolite
p-Hydroxymandelic acid
Cat.No: T5263
Synonym: 4-羟基扁桃酸,4-Hydroxymandelic acid
Target: Others, Endogenous Metabolite
(S)-(-)-Phenylethanol
Cat.No: T4784
Synonym: (S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol
Target: Others, Endogenous Metabolite
Calcium 2-hydroxy-4-(methylthio)butanoate
Cat.No: T5082
Synonym: 羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt
Target: Others, Endogenous Metabolite
Nobiletin
Cat.No: T2834
Synonym: Hexamethoxyflavone,川陈皮素,川皮苷
Target: Apoptosis, MMP, Reactive Oxygen Species, ROR, Autophagy
3-Methoxyphenylacetic acid
Cat.No: Fr13883
Synonym:
Target: Others
3-Ethoxy-3-oxopropanoic acid
Cat.No: T4773
Synonym: Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯
Target: Others, Endogenous Metabolite
Methyl Vanillate
Cat.No: T2818
Synonym:
Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite
N-Acetyl-L-leucine
Cat.No: T4798
Synonym:
Target: Others, Endogenous Metabolite
Diethyl oxalpropionate
Cat.No: T4768
Synonym: 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE
Target: Others, Endogenous Metabolite
Itaconic acid
Cat.No: T4837
Synonym: methylene-butanedioicaci,衣康酸
Target: Others, Endogenous Metabolite
Alloxan
Cat.No: T7814L
Synonym: NSC 7169,NSC7169,NSC-7169
Target:
Libramycin A
Cat.No: T32740
Synonym:
Target:
Juzirine
Cat.No: T32329
Synonym:
Target:
Mammea A/BA
Cat.No: T73068
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01089 FGF-1 Protein, Mouse, Rat, Recombinant

fibroblast growth factor 1 (acidic)

Mouse,Rat E. coli
FGF-1 Protein, Mouse, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P61148.
TMPY-00756 FGF-1 Protein, Human, Recombinant

AFGF,ECGF-beta,ECGFB,fibroblast growth factor 1 (acidic<...

Human E. coli
FGF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P05230-1.
TMPY-03477 FGF-1 Protein, Cynomolgus, Recombinant

fibroblast growth factor 1 (acidic)

Cynomolgus E. coli
FGF-1 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa.
TMPJ-00846 GFAP Protein, Human, Recombinant (His)

Glial Fibrillary Acidic Protein,GFAP

Human E. coli
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desm...
TMPY-03622 FGF-1 Protein, Canine, Recombinant

fibroblast growth factor 1 (acidic)

Canine E. coli
FGF-1 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is A0A8C0QGP1.
TMPJ-01085 DPT Protein, Human, Recombinant (hFc & His)

TRAMP and DPT,Tyrosine-rich acidic matrix protein,D...

Human HEK293 Cells
Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. ...
TMPY-04814 SPARC Protein, Rat, Recombinant (His)

SPARC,secreted protein, acidic, cysteine-rich (oste...

Rat HEK293 Cells
SPARC Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.8 kDa.
TMPY-03048 PRAP1 Protein, Human, Recombinant (mFc)

UPA,proline-rich acidic protein 1,PRO1195

Human HEK293 Cells
PRAP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.4 kDa and the accession number is AAL16670.1.
TMPK-01127 AMCase/CHIA Protein, Mouse, Recombinant (His)

CHIT2,Chia1,AMCase,YNL,Acidic mammalian chitinase,C...

Mouse HEK293 Cells
Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. The expression of AMCase and CHIT-1 were differently modulated in HMMs at different stage of maturation.
TMPY-03076 PRAP1 Protein, Human, Recombinant (His)

UPA,PRO1195,proline-rich acidic protein 1

Human HEK293 Cells
PRAP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is AAL16670.1.
TMPY-02668 NAALADL1 Protein, Mouse, Recombinant (His)

N-acetylated alpha-linked acidic dipeptidase-like 1...

Mouse HEK293 Cells
NAALADL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80 kDa and the accession number is Q7M758.
TMPK-01154 AMCase/CHIA Protein, Human, Recombinant (His)

YNL,AMCase,Chia1,CHIA,Acidic mammalian chitinase,EC...

Human HEK293 Cells
Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages'...
TMPJ-01369 DPT Protein, Mouse, Recombinant (hFc)

EQ-1,Early quiescence protein 1,TRAMP,Tyrosine-rich acid...

Mouse HEK293 Cells
Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growths such as leiomyoma and scar tissue, inhibits cell proliferation, accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation, Dermatopontin deficient mice exhibit altered collagen matrix deposition and organization. Dermatopontin s...
TMPY-01215 NAALADL1 Protein, Human, Recombinant (His)

N-acetylated alpha-linked acidic dipeptidase-like 1...

Human HEK293 Cells
NAALADL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80 kDa and the accession number is Q9UQQ1-1.
TMPY-02010 DMP1 Protein, Human, Recombinant (His)

ARHR,dentin matrix acidic phosphoprotein 1,ARHP,DMP...

Human HEK293 Cells
Dentin matrix acidic phosphoprotein (DMP1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. DMP1 contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nu...
TMPY-01182 SPARC Protein, Human, Recombinant (His)

BM-40,ON,SPARC,secreted protein, acidic, cysteine-r...

Human HEK293 Cells
SPARC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is P09486.
TMPY-01796 SPARC Protein, Mouse, Recombinant (His)

AA517111,secreted protein, acidic, cysteine-rich (o...

Mouse HEK293 Cells
SPARC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is P07214.
TMPH-02357 Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His)

H3N2 E. coli
Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession number is Q9IQ47.
TMPJ-00650 FIBP Protein, Human, Recombinant

FIBP,aFGF Intracellular-Binding Protein,FGF-1 Intracellular-...

Human E. coli
Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds ...
TMPH-02356 Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His)

H1N1 P. pastoris (Yeast)
Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is A4U6V9.
TMPY-01927 ANP32A Protein, Human, Recombinant (His & GST)

MAPM,PP32,I1PP2A,C15orf1,LANP,HPPCn,PHAPI,acidic (l...

Human E. coli
acidic leucine-rich nuclear phosphoprotein 32 family member A, also known as acidic nuclear phosphoprotein pp32, Leucine-rich acidic nuclear protein, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI and ANP32A, is a nucleus, cytoplasm and endoplasmic reticulum. ANP32A / LANP is expressed in all tissues tested. It is highly expressed in kidney and skeletal muscle, moderate levels of expression is in brain, placenta and panc...
TMPY-03221 Intrinsic Factor Protein, Human, Recombinant (His)

IF,IFMH,gastric intrinsic factor (vitamin B synthesis),INF,T...

Human HEK293 Cells
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to...
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant

Fibroblast Growth Factor 2,bFGF,HBGF-2,Basic Fibroblast Grow...

Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari...
TMPH-00627 GAD-alpha Protein, E. coli, Recombinant (His)

E. coli E. coli
Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.
TMPH-02215 TCN1 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPH-02216 TCN1 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPH-03551 Exfoliative toxin A Protein, S. aureus, Recombinant (His)

Staphylococcus aureus E. coli
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS).
TMPH-02162 Synaptotagmin-1 Protein, Human, Recombinant (His)

Human E. coli
Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at leas...
TMPH-02681 GPX7 Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. GPX7 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is Q99LJ6.
TMPH-02680 QPCT Protein, Mouse, Recombinant (His & Myc)

Mouse HEK293 Cells
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 41.6 kDa and the accession number is Q9CYK2.
TMPH-00083 Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

ERD14,Dehydrin ERD14

Arabidopsis thaliana E. coli
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is P42763.
TMPH-02679 QPCT Protein, Mouse, Recombinant (His)

Mouse P. pastoris (Yeast)
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is Q9CYK2.
TMPH-03552 Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc)

Staphylococcus aureus E. coli
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS). Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.8 kDa and the accession number is P09332.
TMPK-00657 SPARC Protein, Cynomolgus, Recombinant (His)

BM-40,EGM_15571,SPARC,ON

Cynomolgus HEK293 Cells
Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM40) is one of the most abundant non-collagenous protein expressed in mineralized tissues.The capacity of SPARC to influence pathways involved in extracellular matrix assembly such as procollagen processing and collagen fibril formation as well as the capacity to influence osteoblast differentiation and osteoclast activity will be addressed.
TMPK-01095 MEPE Protein, Mouse, Recombinant (His)

Osteoregulin,MEPE,OF45

Mouse HEK293 Cells
Matrix extracellular phosphoglycoprotein (MEPE) is expressed in bone and teeth where it has multiple functions. The C-terminus of MEPE contains a mineral-binding, acidic serine- and aspartate-rich motif (ASARM) that is also present in other noncollagenous proteins of mineralized tissues.MEPE-derived ASARM peptides function in phosphate homeostasis and direct inhibition of bone mineralization in a phosphorylation-dependent manner.
TMPH-03691 VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc)

VSIV E. coli
Attaches the virus to host cellular receptor, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane. VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is P0C2X0.
TMPH-03219 Rabies virus (RABV) (strain India) Glycoprotein (His)

RABV P. pastoris (Yeast)
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03158 PAD Protein, Porphyromonas gingivalis, Recombinant (His)

Porphyromonas gingivalis E. coli
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig...
TMPK-00401 FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD1,KGFR,TK14,FGFR2 α (IIIb),...

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPH-03390 TRPV2 Protein, Rat, Recombinant (His)

Rat E. coli
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. TRPV2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 88.2 kDa and th...
TMPH-03221 Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)

RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03223 Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)

RABV Baculovirus Insect Cells
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPJ-00508 CTSL Protein, Human, Recombinant (His)

CTSL,CTSL1,Cathepsin L1,Major Excreted Protein,MEP

Human HEK293 Cells
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the maj...
TMPH-02621 DAO Protein, Mouse, Recombinant (His)

DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase

Mouse E. coli
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system...
TMPK-00391 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

HSFGFR3EX,FGFR3,FGF R3,ACH,CD333,FGFR3 β (IIIb),EC 2.7.10,CE...

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p...
TMPJ-00523 SAA2 Protein, Human, Recombinant (His)

SAA2,SAA,Serum Amyloid A2

Human E. coli
Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA...
TMPH-02431 Legumain Protein, Cynomolgus, Recombinant (His & Myc)

Cynomolgus Baculovirus Insect Cells
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Legumain Protein, Cynomolg...
TMPJ-00964 PRCP Protein, Human, Recombinant (His)

PCP,Proline Carboxypeptidase,PRCP,Lysosomal Pro-X Carboxypep...

Human HEK293 Cells
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been s...
TMPH-02432 Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc)

Cynomolgus E. coli
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Legumain Protein, Cynomolg...
TMPH-03224 Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)

RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
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重组蛋白

FGF-1 Protein, Mouse, Rat, Recombinant
Cat.No: TMPY-01089
Species: Mouse,Rat
Expression System: E. coli
FGF-1 Protein, Human, Recombinant
Cat.No: TMPY-00756
Species: Human
Expression System: E. coli
FGF-1 Protein, Cynomolgus, Recombinant
Cat.No: TMPY-03477
Species: Cynomolgus
Expression System: E. coli
GFAP Protein, Human, Recombinant (His)
Cat.No: TMPJ-00846
Species: Human
Expression System: E. coli
FGF-1 Protein, Canine, Recombinant
Cat.No: TMPY-03622
Species: Canine
Expression System: E. coli
DPT Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-01085
Species: Human
Expression System: HEK293 Cells
SPARC Protein, Rat, Recombinant (His)
Cat.No: TMPY-04814
Species: Rat
Expression System: HEK293 Cells
PRAP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03048
Species: Human
Expression System: HEK293 Cells
AMCase/CHIA Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01127
Species: Mouse
Expression System: HEK293 Cells
PRAP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03076
Species: Human
Expression System: HEK293 Cells
NAALADL1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02668
Species: Mouse
Expression System: HEK293 Cells
AMCase/CHIA Protein, Human, Recombinant (His)
Cat.No: TMPK-01154
Species: Human
Expression System: HEK293 Cells
DPT Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01369
Species: Mouse
Expression System: HEK293 Cells
NAALADL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01215
Species: Human
Expression System: HEK293 Cells
DMP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02010
Species: Human
Expression System: HEK293 Cells
SPARC Protein, Human, Recombinant (His)
Cat.No: TMPY-01182
Species: Human
Expression System: HEK293 Cells
SPARC Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01796
Species: Mouse
Expression System: HEK293 Cells
Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His)
Cat.No: TMPH-02357
Species: H3N2
Expression System: E. coli
FIBP Protein, Human, Recombinant
Cat.No: TMPJ-00650
Species: Human
Expression System: E. coli
Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His)
Cat.No: TMPH-02356
Species: H1N1
Expression System: P. pastoris (Yeast)
ANP32A Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-01927
Species: Human
Expression System: E. coli
Intrinsic Factor Protein, Human, Recombinant (His)
Cat.No: TMPY-03221
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00037
Species: Mouse
Expression System: E. coli
GAD-alpha Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00627
Species: E. coli
Expression System: E. coli
TCN1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02215
Species: Human
Expression System: P. pastoris (Yeast)
TCN1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02216
Species: Human
Expression System: E. coli
Exfoliative toxin A Protein, S. aureus, Recombinant (His)
Cat.No: TMPH-03551
Species: Staphylococcus aureus
Expression System: E. coli
Synaptotagmin-1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02162
Species: Human
Expression System: E. coli
GPX7 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02681
Species: Mouse
Expression System: E. coli
QPCT Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02680
Species: Mouse
Expression System: HEK293 Cells
Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Cat.No: TMPH-00083
Species: Arabidopsis thaliana
Expression System: E. coli
QPCT Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02679
Species: Mouse
Expression System: P. pastoris (Yeast)
Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc)
Cat.No: TMPH-03552
Species: Staphylococcus aureus
Expression System: E. coli
SPARC Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00657
Species: Cynomolgus
Expression System: HEK293 Cells
MEPE Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01095
Species: Mouse
Expression System: HEK293 Cells
VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc)
Cat.No: TMPH-03691
Species: VSIV
Expression System: E. coli
Rabies virus (RABV) (strain India) Glycoprotein (His)
Cat.No: TMPH-03219
Species: RABV
Expression System: P. pastoris (Yeast)
PAD Protein, Porphyromonas gingivalis, Recombinant (His)
Cat.No: TMPH-03158
Species: Porphyromonas gingivalis
Expression System: E. coli
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00401
Species: Human
Expression System: HEK293 Cells
TRPV2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03390
Species: Rat
Expression System: E. coli
Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)
Cat.No: TMPH-03221
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)
Cat.No: TMPH-03223
Species: RABV
Expression System: Baculovirus Insect Cells
CTSL Protein, Human, Recombinant (His)
Cat.No: TMPJ-00508
Species: Human
Expression System: HEK293 Cells
DAO Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02621
Species: Mouse
Expression System: E. coli
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00391
Species: Human
Expression System: HEK293 Cells
SAA2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00523
Species: Human
Expression System: E. coli
Legumain Protein, Cynomolgus, Recombinant (His & Myc)
Cat.No: TMPH-02431
Species: Cynomolgus
Expression System: Baculovirus Insect Cells
PRCP Protein, Human, Recombinant (His)
Cat.No: TMPJ-00964
Species: Human
Expression System: HEK293 Cells
Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-02432
Species: Cynomolgus
Expression System: E. coli
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)
Cat.No: TMPH-03224
Species: RABV
Expression System: E. coli
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