Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T16667 | PROTAC Sirt2 Degrader-1
化合物 T16667
|
2098487-75-1 | 98% |
|
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a b... | ||||
T17249 | VZ185
化合物 T17249
|
2306193-61-1 | 98% |
|
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively). | ||||
T11292 | FKBP12 PROTAC dTAG-7
化合物 T11292
|
2064175-32-0 | 98% |
|
FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET ... | ||||
T5438 | PROTAC CDK9 Degrader-1
化合物PROTAC CDK9 Degrader-1
|
2118356-96-8 | 98% |
|
PROTAC CDK9 Degrader-1 是一种选择性 CDK9 降解剂,是由Cereblon 配体和CDK 配体相连的PROTAC。 | ||||
T13839 | PROTAC ER Degrader-4
化合物 T13839
|
2361114-15-8 | 98% |
|
PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM). | ||||
T11664 | INY-03-041
化合物 T11664
|
T11664 | 98% |
|
INY-03-041, a potent and highly selective PROTAC-based pan-AKT degrader, inhibits AKT1, AKT2, and AKT3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively. Th... | ||||
T12556 | PROTAC B-Raf degrader 1
化合物 T12556
|
2364367-27-9 | 98% |
|
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity. | ||||
T13846 | PROTAC RIPK degrader-2
化合物 T13846
|
1801547-16-9 | 98% |
|
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation. | ||||
T13849 | PROTAC BET Degrader-1
化合物 T13849
|
2093386-22-0 | 98% |
|
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC. | ||||
T18631 | PROTAC MDM2 Degrader-1
化合物 T18631
|
2249944-98-5 | 98% |
|
PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a... | ||||
T18633 | PROTAC MDM2 Degrader-3
化合物 T18633
|
2249750-23-8 | 98% |
|
PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 l... | ||||
T18607 | PROTAC ER Degrader-3
化合物 T18607
|
2158322-29-1 | 98% |
|
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to a... | ||||
T17910 | (S,R,S)-AHPC-PEG2-C4-Cl
化合物 T17910
|
1835705-57-1 | 98% |
|
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capa... | ||||
T17911 | (S,R,S)-AHPC-C6-PEG3-C4-Cl
化合物 T17911
|
1835705-55-9 | 98% |
|
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl i... | ||||
T13842 | PROTAC IRAK4 degrader-1
化合物 T13842
|
2360533-90-8 | 98% |
|
PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4). | ||||
T13835 | PROTAC BRD4 Degrader-3
化合物 T13835
|
2313234-00-1 | 98% |
|
PROTAC BRD4 Degrader-3 is an efficacious degrader of PROTAC BRD4. | ||||
T13785 | MZP-54
化合物 T13785
|
2010159-47-2 | 98% |
|
MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2) | ||||
T14549 | BETd-246
化合物 T14549
|
2140289-17-2 | 98% |
|
BETd-246 is an inhibitor of second-generation and PROTAC-based BET bromodomain (BRD), show antitumor activity. | ||||
T12560 | PROTAC BRD9 Degrader-1
化合物 T12560
|
2097971-01-0 | 98% |
|
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM. | ||||
T16701 | QCA570
化合物 T16701
|
2207569-08-0 | 98% |
|
QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein). |