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PROTAC Selection

PROTAC Selection

Cat. No. Product Name CAS No. Purity Chemical Structure
T31221L DBRD9 HCl
化合物dBRD9盐酸盐
2341840-98-8 99.81%
dBRD9 HCl 是一种PROTAC,包含cereblon E3连接酶配体与BRD9抑制剂BI 7273。dBRD9 HCl 是有效和选择性的BRD9降解剂,在MOLM-13细胞中IC50的为56.6nM。dBRD9 HCl 在浓度高达5μM 时不会降解BRD4或BRD7。dBRD9 HCl 在人AML 细胞系中显示出...
T16667 PROTAC Sirt2 Degrader-1
化合物 T16667
2098487-75-1 98%
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a b...
T17249 VZ185
化合物 T17249
2306193-61-1 98%
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).
T11292 FKBP12 PROTAC dTAG-7
化合物 T11292
2064175-32-0 98%
FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin l...
T5438 PROTAC CDK9 Degrader-1
化合物PROTAC CDK9 Degrader-1
2118356-96-8 98%
PROTAC CDK9 Degrader-1 是一种选择性 CDK9 降解剂,是由Cereblon 配体和CDK 配体相连的PROTAC。
T13839 PROTAC ER Degrader-4
化合物 T13839
2361114-15-8 98%
PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).
T11664 INY-03-041
化合物 T11664
T11664 98%
INY-03-041 inhibits AKT1, AKT2 and AKT3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively. INY-03-041 is a potent, highly selective and PROTAC-based pan-AKT ...
T12556 PROTAC B-Raf degrader 1
化合物 T12556
2364367-27-9 98%
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
T13846 PROTAC RIPK degrader-2
化合物 T13846
1801547-16-9 98%
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.
T13849 PROTAC BET Degrader-1
化合物 T13849
2093386-22-0 98%
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
T18631 PROTAC MDM2 Degrader-1
化合物 T18631
2249944-98-5 98%
PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a...
T18633 PROTAC MDM2 Degrader-3
化合物 T18633
2249750-23-8 98%
PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 l...
T18607 PROTAC ER Degrader-3
化合物 T18607
2158322-29-1 98%
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, is a compound derived from patent WO2017201449A1, specifically compound LP2. PAC serves as the li...
T17910 (S,R,S)-AHPC-PEG2-C4-Cl
化合物 T17910
1835705-57-1 98%
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capa...
T17911 (S,R,S)-AHPC-C6-PEG3-C4-Cl
化合物 T17911
1835705-55-9 98%
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl i...
T13842 PROTAC IRAK4 degrader-1
化合物 T13842
2360533-90-8 98%
PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).
T13835 PROTAC BRD4 Degrader-3
化合物 T13835
2313234-00-1 98%
PROTAC BRD4 Degrader-3 is an efficacious degrader of PROTAC BRD4.
T13785 MZP-54
化合物 T13785
2010159-47-2 98%
MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)
T14549 BETd-246
化合物 T14549
2140289-17-2 98%
BETd-246 is an inhibitor of second-generation and PROTAC-based BET bromodomain (BRD), show antitumor activity.
T12560 PROTAC BRD9 Degrader-1
化合物 T12560
2097971-01-0 98%
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
dBRD9 HCl
T31221L
dBRD9 HCl 是一种PROTAC,包含cereblon E3连接酶配体与BRD9抑制剂BI 7273。dBRD9 HCl 是有效和选择性的BRD9降解剂,在MOLM-13细胞中IC50的为56.6nM。dBRD9 HCl 在浓度高达5μM 时不会降解BRD4或BRD7。dBRD9 HCl 在人AML 细胞系中显示出...
PROTAC Sirt2 Degrader-1
T16667
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a b...
VZ185
T17249
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).
FKBP12 PROTAC dTAG-7
T11292
FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin l...
PROTAC CDK9 Degrader-1
T5438
PROTAC CDK9 Degrader-1 是一种选择性 CDK9 降解剂,是由Cereblon 配体和CDK 配体相连的PROTAC。
PROTAC ER Degrader-4
T13839
PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).
INY-03-041
T11664
INY-03-041 inhibits AKT1, AKT2 and AKT3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively. INY-03-041 is a potent, highly selective and PROTAC-based pan-AKT ...
PROTAC B-Raf degrader 1
T12556
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
PROTAC RIPK degrader-2
T13846
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.
PROTAC BET Degrader-1
T13849
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
PROTAC MDM2 Degrader-1
T18631
PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a...
PROTAC MDM2 Degrader-3
T18633
PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 l...
PROTAC ER Degrader-3
T18607
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, is a compound derived from patent WO2017201449A1, specifically compound LP2. PAC serves as the li...
(S,R,S)-AHPC-PEG2-C4-Cl
T17910
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capa...
(S,R,S)-AHPC-C6-PEG3-C4-Cl
T17911
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl i...
PROTAC IRAK4 degrader-1
T13842
PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).
PROTAC BRD4 Degrader-3
T13835
PROTAC BRD4 Degrader-3 is an efficacious degrader of PROTAC BRD4.
MZP-54
T13785
MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)
BETd-246
T14549
BETd-246 is an inhibitor of second-generation and PROTAC-based BET bromodomain (BRD), show antitumor activity.
PROTAC BRD9 Degrader-1
T12560
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
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