Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Iliparcil 是一种具有口服活性的抗血栓化合物。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,490 | 现货 | ||
5 mg | ¥ 3,750 | 现货 | ||
10 mg | ¥ 5,390 | 现货 | ||
25 mg | ¥ 8,330 | 现货 | ||
50 mg | ¥ 11,200 | 现货 | ||
100 mg | ¥ 14,900 | 现货 | ||
500 mg | ¥ 29,700 | 现货 |
产品描述 | Iliparcil is an antithrombotic compound with oral activity. |
体内活性 | The effect of Iliparcil, a new orally active beta-D-xyloside venous antithrombotic, was studied on the thrombosis following thrombolytic therapy in rats, using a modified Umetsu model. The compound was administered by oral route prior to thrombolytic therapy, which consisted of administering a combination of heparin and urokinase (H/U) at 37.5 and 70,000 IU/kg, respectively. Time to occlusion increased from 3.9 min with saline to 10.5 min following H/U injection. When Iliparcil (30 mg/kg, oral route) was administered 4 h before H/U injection, the time to occlusion was increased by 250% compared with H/U alone (p < 0.001). Similarly, dermatan sulfate (DS), administered intravenously (3 mg/kg) 5 min before thrombus induction, also increased the time to occlusion (300% compared with H/U alone; p < 0.001). It was also shown that times to occlusion following Iliparcil or DS treatments were still increased even when heparin dosage was decreased.[1] |
分子量 | 338.38 |
分子式 | C16H18O6S |
CAS No. | 137214-72-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (147.76 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.9553 mL | 14.7763 mL | 29.5526 mL | 73.8814 mL |
5 mM | 0.5911 mL | 2.9553 mL | 5.9105 mL | 14.7763 mL | |
10 mM | 0.2955 mL | 1.4776 mL | 2.9553 mL | 7.3881 mL | |
20 mM | 0.1478 mL | 0.7388 mL | 1.4776 mL | 3.6941 mL | |
50 mM | 0.0591 mL | 0.2955 mL | 0.5911 mL | 1.4776 mL | |
100 mM | 0.0296 mL | 0.1478 mL | 0.2955 mL | 0.7388 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Iliparcil 137214-72-3 Others Inhibitor inhibitor inhibit