Fuberidazole

Name: Fuberidazole
Brand: TargetMol
SKU: T19673
Price: 291 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 98.95%

货号 T19673Cas号 3878-19-1

别名 麦穗灵

Fuberidazole 是一种抗真菌剂。

Fuberidazole

一键复制产品信息

很棒

纯度: 98.95%

货号 T19673 别名 麦穗灵Cas号 3878-19-1

Fuberidazole 是一种抗真菌剂。

规格	价格	库存
10 mg	¥ 291	现货
25 mg	¥ 418	现货
50 mg	¥ 544	现货
100 mg	¥ 671	现货

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产品介绍

Fuberidazole AI Summary

Fuberidazole exhibits diverse bioactivities across several assays. It shows inhibition of Co2+ loaded MetAP expressed in Escherichia coli, with 10.38% inhibition at a 10 μM concentration and an IC50 value greater than 10,000 nM. At a 25 μM concentration, it inhibits Escherichia coli MetAP by 26.0% and Staphylococcus aureus MetAP by 10.0%. The compound also inhibits recombinant soluble epoxide hydrolase with an IC50 value of 207,000 nM. In human MCF7 cells, Fuberidazole inhibits VEGF production with a 15.0% inhibition rate after 24 hours and exhibits cytotoxicity with an IC50 value of 21.5 μg/mL after 48 hours as measured by the sulforhodamine B assay. It demonstrates CYP3A4 inhibition with an IC50 value greater than 10,000 nM, indicating weak inhibition, and suggests potential interactions with retinoic acid metabolism. For cytotoxicity, it has IC50 values of 105,640 nM against MCF7 cells and 102,530 nM against HepG2 cells, and at its cytotoxic IC50 concentration, it reduces VEGFR2 protein expression in MCF7 cells by 43% after 24 hours..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Fuberidazole is an antifungal agent.
别名	麦穗灵

化学信息

分子量	184.19
分子式	C₁₁H₈N₂O
CAS No.	3878-19-1
Smiles	N1C2=CC=CC=C2N=C1C1=CC=CO1
密度	1.286g/cm3
颜色	Yellow
物理性状	Solid

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	H2O: 0.07 mg/mL (0.38 mM), when pH is adjusted to 7. DMSO: 55 mg/mL (298.6 mM), Sonication is recommended.
体内实验配方	10% DMSO+90% Saline: 5 mg/mL (27.15 mM), Sonication is recommeded. 请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。