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顶部生物活性储存和溶解信息计算器

Anti-MMP-13 Polyclonal Antibody

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产品编号 TMAB-01151
别名 MMP13, Matrix metalloproteinase-13 (MMP-13), Collagenase 3

Anti-MMP-13 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MMP-13。Anti-MMP-13 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-MMP-13 Polyclonal Antibody

Anti-MMP-13 Polyclonal Antibody

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产品编号 TMAB-01151 别名 MMP13, Matrix metalloproteinase-13 (MMP-13), Collagenase 3

Anti-MMP-13 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MMP-13。Anti-MMP-13 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

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50 μL
¥ 1,175
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100 μL
¥ 1,960
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200 μL
¥ 2,790
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产品介绍

生物活性
产品描述
Anti-MMP-13 Polyclonal Antibody is a Rabbit antibody targeting MMP-13. Anti-MMP-13 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名MMP13, Matrix metalloproteinase-13 (MMP-13), Collagenase 3
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Rabbit)
验证活性
1. Tissue/cell: human bladder carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-MMP-13 Polyclonal Antibody, Unconjugated (TMAB-01151) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Generously provided by Markus Linder from Medical University Vienna as part of the Bioss Discovery Program. Formalin-fixed, paraffin embedded, and decalcified in EDTA mouse bone labeled with Anti-MMP-13 Polyclonal Antibody, Unconjugated (TMAB-01151) at 1:200 followed by conjugation to the secondary antibody and DAb staining.
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix (Probable).
组织特异性Seems to be specific to breast carcinomas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human MMP13
抗原种属
Human
基因名称
MMP13
基因ID
4322
蛋白名称
Collagenase 3
Uniprot ID
P45452
研究领域
MMPs,MMPs,MMPs,MMP,MMPs,Tumor biomarkers ELISA kits,MMP
功能
Degrades collagen type I. Does not act on gelatin or casein. Could have a role in tumoral process.
化学信息
分子量Theoretical: 52 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

MMP-13MMP 13Collagenase3

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