dopa decarboxylase

L-(-)-α-Methyldopa (MK-351) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂，对 α2- adrenergic receptors 有选择性。

Benserazide hydrochloride (Ro 4-4602) 是一种芳香族 L-氨基酸脱羧酶（AADC）的抑制剂，常用于帕金森病。

Methyldopa hydrate (MK-351 hydrate) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是一种 α-肾上腺素能激动剂，对α2-adrenergic receptors 有选择性。

L-DOPA（Levodopa）是一种具有口服活性的神经递质多巴胺的代谢前体，能够透过血脑屏障并在大脑中转化为多巴胺，具有抗痛觉过敏作用，在帕金森氏病研究中具有潜力，并可用于诱导帕金森病模型。

Carbidopa monohydrate (S(-)-Carbidopa) 是一种外周型脱羧酶抑制剂，可用于帕金森病的研究。它是一种选择性芳香烃受体 (AhR) 调节剂。它抑制胰腺癌细胞和肿瘤生长。

Benserazide is an inhibitor of dopa decarboxylase. It is often given with levodopa in the treatment of Parkinson's to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system an

L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts

Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot

Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml).1 It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg. |1. Chimura, H., Sawa, T., Takita, T., et al. Methylspinazarin and dihydromethylspinazarin, gatechol-O-methyl transerfase inhibitors produced by Streptomyces. J. Antibiot. 26(2), 112-114 (1973).

Dopamine 3-O-sulfate是Dopamine的磺化代谢物，主要存在于血浆中。Dopamine 3-O-sulfate也是帕金森患者L-dopa的代谢终产物。

Benserazide-d3 HCl 是 Benserazide HCl 的氘代化合物。Benserazide HCl 的 CAS 号为 14919-77-8。Benserazide hydrochloride 是一种芳香族 L-氨基酸脱羧酶（AADC）的抑制剂，常用于帕金森病。

L-DOPA-2,5,6-d3是L-Dopa的氘代标记物，可用于同位素示踪。L-DOPA是一种具有口服活性的神经递质多巴胺的代谢前体，能够透过血脑屏障并在大脑中转化为多巴胺，具有抗痛觉过敏作用，可用于研究帕金森病。

Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by