规格

价格

库存

数量

10 mg

¥ 152

现货

25 mg

¥ 230

现货

生物活性

产品描述	Tetradifon is a broad-spectrum organochlorine acaricide insecticide and a potent inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP)，a subunit of ATP synthase. Tetradifon is utilized for controlling a variety of mite pests and inhibiting energy-related mitochondrial activities including ADP-stimulated respiration and ATPase activity with an IC50 range of 4.5-27 nmoL/mg mitochondrial protein; it exerts oligomycin-like effects by inhibiting oxidative phosphorylation, inducing significant oxidative stress, and interfering with bone metabolism, making it a compound of interest for researching mitochondrial function, bone remodeling mechanisms, and nephrotoxicity.
体内活性	Tetradifon（24.3mg/kg，口服灌胃，90天）处理雌性Wistar大鼠，第12周时，肌酐/尿素水平升高24%/43%，肾小球硬化率升高至22%，间质纤维化指数升高200%，肾脏SOD/GPx活性降低32%/17%，维生素C含量降低31%。[5]
别名	三氯杀螨砜, Roztozol, Roztoczol extra, Roztoczol

化学信息

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 40 mg/mL (112.34 mM), Sonication is recommended.

体内实验配方

10% DMSO+90% Corn Oil: 2 mg/mL (5.62 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

Tetradifon